Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ACE | P12821 | 2/20 | 0.61 |
| ▸ | RNPEP | Q9H4A4 | 1/20 | 0.52 |
| ▸ | LMNA | P02545 | 1/20 | 0.50 |
| ▸ | FOLH1 | Q04609 | 1/20 | 0.49 |
| ▸ | FNTA | P49354 | 2/20 | 0.47 |
| ▸ | FNTB | P49356 | 2/20 | 0.47 |
| ▸ | PGGT1B | P53609 | 1/20 | 0.47 |
| ▸ | LTA4H | P09960 | 1/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.47 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.47 |
| ▸ | MME | P08473 | 1/20 | 0.47 |
| ▸ | CPA1 | P15085 | 1/20 | 0.47 |
| ▸ | ACE2 | Q9BYF1 | 1/20 | 0.47 |
| ▸ | CA2 | P00918 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29204872 | 0.86 | LMNA (0.53) | LMNAFOLH1FNTAFNTBPGGT1B | |
| SCHEMBL11105424 | 0.85 | ACE (0.46) | ACERNPEPFNTAFNTBPGGT1B | |
| SCHEMBL4957057 | 0.84 | LMNA (0.51) | LMNAFOLH1FNTAFNTBPGGT1B | |
| SCHEMBL4953101 | 0.84 | LMNA (0.51) | LMNAFOLH1FNTAFNTBPGGT1B | |
| SCHEMBL29851702 | 0.84 | LMNA (0.51) | LMNAFOLH1FNTAFNTBPGGT1B | |
| SCHEMBL4572626 | 0.84 | LMNA (0.51) | LMNAFOLH1FNTAFNTBPGGT1B | |
| SCHEMBL9068525 | 0.83 | FNTA (0.51) | ACELMNAFNTAFNTBPGGT1B | |
| SCHEMBL3101246 | 0.83 | FNTA (0.50) | LMNAFOLH1FNTAFNTBPGGT1B | |
| SCHEMBL1859748 | 0.83 | FNTA (0.50) | LMNAFOLH1FNTAFNTBPGGT1B | |
| SCHEMBL9400601 | 0.83 | FNTA (0.50) | LMNAFOLH1FNTAFNTBPGGT1B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4460601-A | Dipeptides having a methionine residue and possessing a protective action for the liver | MAGGIONI FARMACEUTICI, S.P.A. (IT) | 1984-07-17 | — | — | US | disclosed |