Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 4/20 | 0.50 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.50 |
| ▸ | MAPT | P10636 | 4/20 | 0.50 |
| ▸ | THRB | P10828 | 3/20 | 0.50 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.50 |
| ▸ | GAA | P10253 | 3/20 | 0.50 |
| ▸ | GFER | P55789 | 2/20 | 0.50 |
| ▸ | ALOX15 | P16050 | 2/20 | 0.50 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.50 |
| ▸ | YWHAG | P61981 | 1/20 | 0.50 |
| ▸ | HTT | P42858 | 2/20 | 0.49 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.44 |
| ▸ | RECQL | P46063 | 2/20 | 0.44 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.44 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.44 |
| ▸ | PKM | P14618 | 2/20 | 0.44 |
| ▸ | POLB | P06746 | 2/20 | 0.44 |
| ▸ | USP2 | O75604 | 1/20 | 0.44 |
| ▸ | APEX1 | P27695 | 1/20 | 0.44 |
| ▸ | BLM | P54132 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11101742 | 0.87 | KDM4E (0.56) | MEN1KMT2AMAPTTHRBKDM4E | |
| SCHEMBL11278156 | 0.85 | MAPT (0.47) | MEN1KMT2AMAPTTHRBKDM4E | |
| SCHEMBL11275759 | 0.84 | MYC (0.49) | KDM4EHSD17B10HTTALDH1A1PKM | |
| SCHEMBL11274927 | 0.82 | LIPG (0.48) | GAAHTTALDH1A1LIPGSMN1; SMN2 | |
| SCHEMBL11277428 | 0.82 | CSNK2A1 (0.44) | KDM4EGAAHTTALDH1A1TDP1 | |
| SCHEMBL11286093 | 0.82 | MYC (0.50) | MEN1KMT2AMAPTKDM4EHTT | |
| SCHEMBL11100693 | 0.82 | MYC (0.50) | MAPTKDM4EHSD17B10ALDH1A1TDP1 | |
| SCHEMBL2336439 | 0.80 | KDM4E (0.76) | MEN1KMT2AMAPTTHRBKDM4E | |
| SCHEMBL11108433 | 0.79 | GAA (0.56) | MEN1KMT2AMAPTTHRBKDM4E | |
| SCHEMBL11100658 | 0.79 | GAA (0.56) | MEN1KMT2AMAPTTHRBKDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0063826-B1 | 2-AMINO-BENZOIC-ACID DERIVATIVES, THEIR PREPARATION AND THEIR USE AS MEDICINES OR INTERMEDIATES | Dr. Karl Thomae GmbH (DE) | 1984-12-05 | — | — | EP | disclosed |
| EP-0023569-B1 | DERIVATIVES OF CARBOXYLIC ACIDS, THEIR PREPARATION AND MEDICAMENTS CONTAINING THEM | Dr. Karl Thomae GmbH (DE) | 1983-06-22 | — | — | EP | disclosed |
| EP-0063826-A2 | 2-Amino-benzoic-acid derivatives, their preparation and their use as medicines or intermediates | Dr. Karl Thomae GmbH (DE) | 1982-11-03 | — | — | EP | disclosed |
| EP-0056144-A1 | Carboxylic acid derivatives, their preparation and use as pharmaceuticals | Dr. Karl Thomae GmbH (DE) | 1982-07-21 | — | — | EP | disclosed |
| EP-0023569-A1 | Derivatives of carboxylic acids, their preparation and medicaments containing them | Dr. Karl Thomae GmbH (DE) | 1981-02-11 | — | — | EP | disclosed |