SCHEMBL1110705

SCHEMBL1110705

CC1C[C@](C)(O)C(=O)[C@@H](O)C1=O

nearest known ligand 0.33

Predicted protein targets (top 3)

geneUniProtsupporting neighboursconfidence
NR2F2 P24468 1/20 0.33
ENO1 P06733 1/20 0.31
PTPN1 P18031 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL1110020 0.81 ENO1 (0.32) NR2F2ENO1PTPN1
SCHEMBL1110119 0.81 ENO1 (0.32) NR2F2ENO1PTPN1
SCHEMBL1110934 0.71 KDM4E (0.35)
SCHEMBL1111175 0.71 KDM4E (0.35)
SCHEMBL8676192 0.70 NR2F2 (0.47) NR2F2PTPN1
SCHEMBL14208305 0.70 NR2F2 (0.47) NR2F2PTPN1
SCHEMBL13811045 0.64
SCHEMBL11260927 0.61 PTPN1 (0.32) PTPN1
SCHEMBL7838483 0.60 ENO1 (0.32) ENO1PTPN1
SCHEMBL8677887 0.60 ENO1 (0.32) ENO1PTPN1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-2279291-A2 COFERONS AND METHODS OF MAKING AND USING THEM Cornell University (US) 2011-02-02 EP disclosed
WO-2009126290-A2 COFERONS AND METHODS OF MAKING AND USING THEM CORNELL UNIVERSITY (US) 2009-10-15 WO disclosed