Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 2/20 | 0.43 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.43 |
| ▸ | NPC1 | O15118 | 4/20 | 0.42 |
| ▸ | RAB9A | P51151 | 4/20 | 0.42 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.42 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.42 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.42 |
| ▸ | MEN1 | O00255 | 1/20 | 0.42 |
| ▸ | HTT | P42858 | 2/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.41 |
| ▸ | TSHR | P16473 | 1/20 | 0.41 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.41 |
| ▸ | NAMPT | P43490 | 1/20 | 0.40 |
| ▸ | GAA | P10253 | 2/20 | 0.39 |
| ▸ | PKM | P14618 | 3/20 | 0.39 |
| ▸ | TAS1R3 | Q7RTX0 | 1/20 | 0.38 |
| ▸ | TAS1R1 | Q7RTX1 | 1/20 | 0.38 |
| ▸ | TAS1R2 | Q8TE23 | 1/20 | 0.38 |
| ▸ | PIK3CD | O00329 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11109009 | 0.86 | HTT (0.43) | KMT2AL3MBTL1SMN1; SMN2NPC1RAB9A | |
| SCHEMBL5531898 | 0.74 | SMN1; SMN2 (0.58) | KMT2AL3MBTL1SMN1; SMN2NPC1RAB9A | |
| SCHEMBL20488237 | 0.73 | KMT2A (0.48) | KMT2AL3MBTL1SMN1; SMN2NPC1RAB9A | |
| SCHEMBL21657732 | 0.70 | ALDH1A1 (0.56) | KMT2AL3MBTL1SMN1; SMN2NPC1RAB9A | |
| SCHEMBL23617578 | 0.70 | KMT2A (0.39) | KMT2AL3MBTL1SMN1; SMN2NPC1RAB9A | |
| SCHEMBL27278396 | 0.69 | HTT (0.67) | KMT2AL3MBTL1SMN1; SMN2NPC1RAB9A | |
| SCHEMBL23617581 | 0.69 | KMT2A (0.40) | KMT2AL3MBTL1SMN1; SMN2NPC1RAB9A | |
| SCHEMBL262323 | 0.68 | — | — | |
| SCHEMBL335332 | 0.68 | — | — | |
| SCHEMBL8021773 | 0.67 | HTT (0.50) | KMT2AL3MBTL1SMN1; SMN2NPC1RAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4477448-A | CONTAIN PYRAZOLE SUBSTITUENTS | SANDOZ LTD. (CH) | 1984-10-16 | — | — | US | disclosed |