Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EGFR | P00533 | 4/20 | 0.57 |
| ▸ | PDE10A | Q9Y233 | 1/20 | 0.55 |
| ▸ | GALR3 | O60755 | 2/20 | 0.54 |
| ▸ | NR2F2 | P24468 | 2/20 | 0.54 |
| ▸ | RAB9A | P51151 | 1/20 | 0.54 |
| ▸ | TSHR | P16473 | 3/20 | 0.53 |
| ▸ | LMNA | P02545 | 3/20 | 0.53 |
| ▸ | HTT | P42858 | 2/20 | 0.53 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.53 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.53 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.50 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.50 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.50 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.50 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.50 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.50 |
| ▸ | CDK1 | P06493 | 1/20 | 0.50 |
| ▸ | KDM4C | Q9H3R0 | 1/20 | 0.49 |
| ▸ | CDK2 | P24941 | 1/20 | 0.49 |
| ▸ | PDE4A | P27815 | 1/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9609203 | 0.84 | GALR3 (0.58) | EGFRGALR3NR2F2RAB9ALMNA | |
| SCHEMBL11104154 | 0.83 | EGFR (0.53) | EGFRGALR3NR2F2RAB9ATSHR | |
| SCHEMBL4032806 | 0.81 | EGFR (0.54) | EGFRGALR3NR2F2RAB9ATSHR | |
| SCHEMBL30983851 | 0.81 | KDM4C (0.72) | EGFRGALR3NR2F2RAB9ATSHR | |
| SCHEMBL783719 | 0.81 | KDM4C (0.72) | EGFRGALR3NR2F2RAB9ATSHR | |
| SCHEMBL11110616 | 0.81 | EGFR (0.54) | EGFRGALR3NR2F2RAB9ATSHR | |
| SCHEMBL23204279 | 0.77 | ALDH1A1 (0.54) | EGFRGALR3NR2F2RAB9ATSHR | |
| SCHEMBL5031499 | 0.77 | EGFR (0.50) | EGFRGALR3NR2F2RAB9ATSHR | |
| SCHEMBL20619314 | 0.77 | EGFR (0.53) | EGFRGALR3NR2F2RAB9ATSHR | |
| SCHEMBL29956286 | 0.77 | EGFR (0.50) | EGFRGALR3NR2F2RAB9ATSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4435402-A | Aminopyrimidine derivatives, processes for their preparation, and fungicidal, insecticidal and acaricidal compositions containing them | SANKYO COMPANY, LIMITED (JP) | 1984-03-06 | — | — | US | disclosed |
| EP-0057440-A1 | Aminopyrimidine derivatives, processes for their preparation, and fungicidal, insecticidal and acaricidal compositions containing them | SANKYO COMPANY LIMITED (JP) | 1982-08-11 | — | — | EP | disclosed |