Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 4/20 | 0.47 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.47 |
| ▸ | GAA | P10253 | 2/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.45 |
| ▸ | RPS6KA3 | P51812 | 1/20 | 0.45 |
| ▸ | RPS6KA2 | Q15349 | 1/20 | 0.45 |
| ▸ | LMNA | P02545 | 1/20 | 0.45 |
| ▸ | POLB | P06746 | 1/20 | 0.45 |
| ▸ | S100A4 | P26447 | 2/20 | 0.45 |
| ▸ | LRRK2 | Q5S007 | 1/20 | 0.45 |
| ▸ | CA1 | P00915 | 1/20 | 0.45 |
| ▸ | CA2 | P00918 | 1/20 | 0.45 |
| ▸ | ALDH3A1 | P30838 | 1/20 | 0.45 |
| ▸ | MEN1 | O00255 | 3/20 | 0.45 |
| ▸ | NPC1 | O15118 | 3/20 | 0.45 |
| ▸ | RAB9A | P51151 | 3/20 | 0.45 |
| ▸ | TDP2 | O95551 | 2/20 | 0.45 |
| ▸ | APAF1 | O14727 | 1/20 | 0.45 |
| ▸ | NSD2 | O96028 | 1/20 | 0.45 |
| ▸ | GALK1 | P51570 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11703854 | 0.88 | MAPT (0.43) | KMT2ASMN1; SMN2GAAALDH1A1RPS6KA3 | |
| SCHEMBL28199493 | 0.85 | KDM4E (0.57) | KMT2ASMN1; SMN2GAAALDH1A1LMNA | |
| SCHEMBL30022123 | 0.85 | POLB (0.54) | KMT2AGAAALDH1A1POLBMEN1 | |
| SCHEMBL13016515 | 0.84 | KDM4E (0.41) | KMT2ASMN1; SMN2GAAALDH1A1LMNA | |
| SCHEMBL30595375 | 0.81 | POLB (0.50) | KMT2AGAAALDH1A1POLBNPC1 | |
| SCHEMBL1001751 | 0.81 | POLB (0.50) | KMT2AGAAALDH1A1POLBLRRK2 | |
| SCHEMBL6193007 | 0.79 | ALDH1A1 (0.49) | KMT2AGAAALDH1A1POLBLRRK2 | |
| SCHEMBL83222 | 0.79 | ALDH1A1 (0.49) | KMT2AGAAALDH1A1POLBLRRK2 | |
| SCHEMBL29643230 | 0.79 | ALDH1A1 (0.49) | KMT2AGAAALDH1A1POLBLRRK2 | |
| SCHEMBL11706050 | 0.79 | CA9 (0.41) | ALDH1A1CA1CA2L3MBTL1MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0099614-A2 | Nitro, amino and aroylamino-N-phenylpyridinamines and their use in a process for preparing pyrido(1,4)benzodiazapines | A.H. ROBINS COMPANY, INCORPORATED (US) | 1984-02-01 | — | — | EP | claimed |
| US-4318925-A | 4-Homoisotwistane derivatives | SUMITOMO CHEMICAL CO., LTD. (JP) | 1982-03-09 | — | — | US | disclosed |