Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 4/20 | 0.62 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.50 |
| ▸ | TSHR | P16473 | 2/20 | 0.44 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.33 |
| ▸ | CETP | P11597 | 2/20 | 0.33 |
| ▸ | SPHK1 | Q9NYA1 | 2/20 | 0.33 |
| ▸ | GMNN | O75496 | 1/20 | 0.33 |
| ▸ | POLB | P06746 | 1/20 | 0.33 |
| ▸ | THPO | P40225 | 1/20 | 0.33 |
| ▸ | MTOR | P42345 | 1/20 | 0.33 |
| ▸ | BLM | P54132 | 1/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.33 |
| ▸ | TP53 | P04637 | 1/20 | 0.33 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.33 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.33 |
| ▸ | MAPT | P10636 | 1/20 | 0.33 |
| ▸ | HTT | P42858 | 1/20 | 0.33 |
| ▸ | UBE2N | P61088 | 1/20 | 0.33 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.32 |
| ▸ | CA1 | P00915 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17526637 | 1.00 | LMNA (0.62) | LMNAALDH1A1TSHRCYP2D6CETP | |
| SCHEMBL17526784 | 1.00 | LMNA (0.62) | LMNAALDH1A1TSHRCYP2D6CETP | |
| SCHEMBL17526548 | 0.98 | LMNA (0.67) | LMNAALDH1A1TSHRCYP2D6CETP | |
| SCHEMBL17526404 | 0.98 | LMNA (0.67) | LMNAALDH1A1TSHRCYP2D6CETP | |
| SCHEMBL17526445 | 0.95 | LMNA (0.56) | LMNAALDH1A1TSHRCETPBLM | |
| SCHEMBL17526539 | 0.95 | LMNA (0.56) | LMNAALDH1A1TSHRCETPBLM | |
| SCHEMBL10834859 | 0.91 | LMNA (0.77) | LMNAALDH1A1TSHRCYP2D6CETP | |
| SCHEMBL17526855 | 0.91 | LMNA (0.70) | LMNAALDH1A1TSHRCYP2D6CETP | |
| SCHEMBL8151154 | 0.88 | LMNA (0.82) | LMNAALDH1A1TSHRCYP2D6CETP | |
| SCHEMBL17526954 | 0.88 | LMNA (0.74) | LMNAALDH1A1TSHRCYP2D6CETP |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0104309-A2 | Catalysts for alkoxylation reactions | VISTA CHEMICAL COMPANY (US) | 1984-04-04 | — | — | EP | disclosed |