Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ERN1 | O75460 | 1/20 | 0.43 |
| ▸ | HSD17B10 | Q99714 | 4/20 | 0.40 |
| ▸ | TP53 | P04637 | 2/20 | 0.40 |
| ▸ | NPFFR1 | Q9GZQ6 | 1/20 | 0.39 |
| ▸ | NPFFR2 | Q9Y5X5 | 1/20 | 0.39 |
| ▸ | BACE1 | P56817 | 1/20 | 0.38 |
| ▸ | RAD52 | P43351 | 3/20 | 0.36 |
| ▸ | PDE10A | Q9Y233 | 2/20 | 0.36 |
| ▸ | DHODH | Q02127 | 2/20 | 0.36 |
| ▸ | MPO | P05164 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.36 |
| ▸ | HPGD | P15428 | 3/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.36 |
| ▸ | GLA | P06280 | 2/20 | 0.36 |
| ▸ | CASP1 | P29466 | 2/20 | 0.36 |
| ▸ | CASP7 | P55210 | 2/20 | 0.36 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.36 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.36 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11110556 | 0.79 | ERN1 (0.39) | ERN1HSD17B10TP53NPFFR1NPFFR2 | |
| SCHEMBL9779309 | 0.78 | TP53 (0.54) | ERN1HSD17B10TP53PDE10ADHODH | |
| SCHEMBL31036205 | 0.78 | TP53 (0.54) | ERN1HSD17B10TP53PDE10ADHODH | |
| SCHEMBL30713425 | 0.75 | DHODH (0.46) | ERN1HSD17B10TP53PDE10ADHODH | |
| SCHEMBL11689100 | 0.71 | HTT (0.53) | ERN1PDE10ADHODHALDH1A1SMN1; SMN2 | |
| SCHEMBL9779119 | 0.71 | SMN1; SMN2 (0.61) | TP53ALDH1A1SMN1; SMN2HPGDKDM4E | |
| SCHEMBL11565856 | 0.71 | GAA (0.45) | ERN1HSD17B10TP53PDE10ADHODH | |
| SCHEMBL851828 | 0.70 | KDM4E (0.44) | ERN1HSD17B10TP53RAD52PDE10A | |
| SCHEMBL311283 | 0.70 | KDM4E (0.44) | ERN1HSD17B10TP53RAD52PDE10A | |
| Acridone SCHEMBL27574706 | 0.70 | KDM4E (0.54) | ERN1HSD17B10TP53RAD52PDE10A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4474952-A | ORGANIC PIGMENTS | CIBA-GEIGY CORPORATION (US) | 1984-10-02 | — | — | US | disclosed |
| US-4367333-A | PLASTICS | CIBA-GEIGY CORPORATION (US) | 1983-01-04 | — | — | US | disclosed |
| US-4366312-A | Metal complexes of isoindolinazines, process for their preparation and use | CIBA-GEIGY CORPORATION (US) | 1982-12-28 | — | — | US | disclosed |