Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TP53 | P04637 | 1/20 | 0.54 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.54 |
| ▸ | DHODH | Q02127 | 4/20 | 0.46 |
| ▸ | PDE10A | Q9Y233 | 3/20 | 0.46 |
| ▸ | ERN1 | O75460 | 1/20 | 0.46 |
| ▸ | CA12 | O43570 | 1/20 | 0.46 |
| ▸ | CA9 | Q16790 | 1/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.45 |
| ▸ | HTT | P42858 | 2/20 | 0.42 |
| ▸ | POLB | P06746 | 1/20 | 0.42 |
| ▸ | TSHR | P16473 | 1/20 | 0.41 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.40 |
| ▸ | MEN1 | O00255 | 1/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31036205 | 1.00 | TP53 (0.54) | TP53HSD17B10DHODHPDE10AERN1 | |
| SCHEMBL30713425 | 0.82 | DHODH (0.46) | TP53HSD17B10DHODHPDE10AERN1 | |
| SCHEMBL11689100 | 0.82 | HTT (0.53) | DHODHPDE10AERN1ALDH1A1HTT | |
| SCHEMBL15782876 | 0.80 | KDM4E (0.49) | TP53HSD17B10DHODHPDE10AERN1 | |
| SCHEMBL12220557 | 0.79 | HSD17B10 (0.62) | TP53HSD17B10DHODHPDE10AALDH1A1 | |
| SCHEMBL11110185 | 0.78 | ERN1 (0.43) | TP53HSD17B10DHODHPDE10AERN1 | |
| SCHEMBL11417466 | 0.78 | ALDH1A1 (0.54) | HSD17B10DHODHALDH1A1HTTPOLB | |
| SCHEMBL11565856 | 0.78 | GAA (0.45) | TP53HSD17B10DHODHPDE10AERN1 | |
| SCHEMBL29860485 | 0.78 | SMN1; SMN2 (0.58) | CA12CA9ALDH1A1POLBMEN1 | |
| SCHEMBL27659536 | 0.78 | SMN1; SMN2 (0.58) | CA12CA9ALDH1A1POLBMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 28 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5066695-A | Plastics; heat resistance, dispersibility | CIBA-GEIGY CORPORATION (US) | 1991-11-19 | — | — | US | disclosed |
| EP-0349489-A2 | Organic macromolecular material containing a hydrazone-based metal complex pigment | CIBA-GEIGY AG (CH) | 1990-01-03 | — | — | EP | disclosed |
| EP-0159962-B1 | FIBRE-REACTIVE CHROMIUM OR COBALT COMPLEXES, THEIR PREPARATION AND THEIR USE | CIBA-GEIGY AG (CH) | 1989-02-08 | — | — | EP | disclosed |
| US-4680385-A | Metal dye complexes containing an azo or azomethine dye and a colorless ligand with the C═N--N═C group | CIBA-GEIGY CORPORATION (US) | 1987-07-14 | — | — | US | disclosed |
| US-4678851-A | FIBER-RACTIVE | CIBA-GEIGY CORPORATION (US) | 1987-07-07 | — | — | US | disclosed |
| EP-0159962-A2 | Fibre-reactive chromium or cobalt complexes, their preparation and their use | CIBA-GEIGY AG (CH) | 1985-10-30 | — | — | EP | disclosed |
| EP-0036834-B1 | PROCESS FOR THE PREPARATION OF METAL COMPLEXES OF ISOINDOLINE AZINES | CIBA-GEIGY AG (CH) | 1983-12-07 | — | — | EP | disclosed |
| US-4362876-A | Preparation of dihydroxyquinoline and certain derivatives | THE SHERWIN-WILLIAMS COMPANY (US) | 1982-12-07 | — | — | US | disclosed |
| US-4349671-A | Process for the production of metal complexes of isoindoline azines | CIBA-GEIGY CORPORATION (US) | 1982-09-14 | — | — | US | disclosed |
| EP-0020302-B1 | NICKEL COMPLEX OF AN ISOINDOLINAZINE, ITS PREPARATION PROCESS, ITS USE FOR PIGMENTING HIGH MOLECULAR ORGANIC MATERIAL AND THIS HIGH MOLECULAR ORGANIC MATERIAL | CIBA-GEIGY AG (CH) | 1982-08-25 | — | — | EP | disclosed |
| US-4144258-A | ORGANIC PIGMENTS FOR POLYMERS | CIBA-GEIGY CORPORATION (US) | 1979-03-13 | — | — | US | disclosed |
| US-4132708-A | Metal complexes of azomethines and process for their manufacture | CIBA-GEIGY CORPORATION (US) | 1979-01-02 | — | — | US | disclosed |
| US-4111947-A | DYES, PLASTICS, LACQUERS | CIBA-GEIGY CORPORATION (US) | 1978-09-05 | — | — | US | disclosed |
| US-4086349-A | Quinolopyran-4-one-2-carboxylic acid derivatives and salts thereof as novel compounds and as medicines for treatment of allergic asthma | MITSUBISHI YUKA PHARMACEUTICAL CO., LTD. (JA) | 1978-04-25 | — | — | US | disclosed |
| US-4065481-A | 1:1-Azomethine-metal-complex dyestuffs | CIBA-GEIGY CORPORATION (US) | 1977-12-27 | — | — | US | disclosed |
| US-4024132-A | Azomethine pigments | CIBA-GEIGY CORPORATION (US) | 1977-05-17 | — | — | US | disclosed |
| US-4022770-A | COLORING | CIBA-GEIGY CORPORATION (US) | 1977-05-10 | — | — | US | disclosed |
| US-4016157-A | COLORING PLASTICS AND LACQUERS | CIBA-GEIGY CORPORATION (US) | 1977-04-05 | — | — | US | disclosed |
| US-3988323-A | PIGMENTS | CIBA-GEIGY CORPORATION (US) | 1976-10-26 | — | — | US | disclosed |
| US-3974149-A | TONERS | CIBA-GEIGY CORPORATION (US) | 1976-08-10 | — | — | US | disclosed |