Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.47 |
| ▸ | MAPT | P10636 | 3/20 | 0.47 |
| ▸ | GLA | P06280 | 2/20 | 0.47 |
| ▸ | CTDSP1 | Q9GZU7 | 2/20 | 0.44 |
| ▸ | MEN1 | O00255 | 1/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.41 |
| ▸ | BLM | P54132 | 2/20 | 0.41 |
| ▸ | GRM1 | Q13255 | 1/20 | 0.41 |
| ▸ | PMP22 | Q01453 | 1/20 | 0.41 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.41 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.41 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.41 |
| ▸ | TSHR | P16473 | 1/20 | 0.41 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.41 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.41 |
| ▸ | RECQL | P46063 | 1/20 | 0.41 |
| ▸ | GAA | P10253 | 2/20 | 0.40 |
| ▸ | APAF1 | O14727 | 1/20 | 0.40 |
| ▸ | TDP2 | O95551 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11112900 | 0.88 | ALDH1A1 (0.42) | ALDH1A1MAPTGLACTDSP1MEN1 | |
| SCHEMBL11106105 | 0.88 | KMT2A (0.45) | ALDH1A1MAPTGLACTDSP1MEN1 | |
| SCHEMBL11112812 | 0.87 | ALDH1A1 (0.48) | ALDH1A1MAPTGLACTDSP1MEN1 | |
| SCHEMBL11104792 | 0.87 | ALDH1A1 (0.41) | ALDH1A1MAPTGLACTDSP1MEN1 | |
| SCHEMBL11107111 | 0.87 | ALDH1A1 (0.39) | ALDH1A1MAPTGLACTDSP1MEN1 | |
| SCHEMBL11104144 | 0.87 | ALDH1A1 (0.39) | ALDH1A1MAPTGLACTDSP1MEN1 | |
| SCHEMBL11107462 | 0.87 | ALPG (0.40) | ALDH1A1MAPTGLACTDSP1MEN1 | |
| SCHEMBL11112755 | 0.87 | ALDH1A1 (0.41) | ALDH1A1MAPTGLACTDSP1MEN1 | |
| SCHEMBL11109868 | 0.86 | MAPT (0.40) | ALDH1A1MAPTGLACTDSP1MEN1 | |
| SCHEMBL11111360 | 0.86 | MAPT (0.42) | ALDH1A1MAPTGLACTDSP1MEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4463001-A | ANTIULCER AGENTS | FARMITALIA CARLO ERBA S.P.A. (IT) | 1984-07-31 | — | — | US | disclosed |