SCHEMBL11110548

SCHEMBL11110548

CN(Cc1ccccc1)C1=CCC(=[N+]=[N-])C=C1

nearest known ligand 0.39

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
TSHR P16473 3/20 0.39
ALDH1A1 P00352 2/20 0.39
AOC3 Q16853 1/20 0.37
CARM1 Q86X55 1/20 0.33
PRMT6 Q96LA8 1/20 0.33
PRMT8 Q9NR22 1/20 0.33
NR1H2 P55055 1/20 0.33
NR1H3 Q13133 1/20 0.33
NPC1 O15118 2/20 0.33
RAB9A P51151 2/20 0.33
LMNA P02545 2/20 0.33
OPRM1 P35372 1/20 0.33
OPRL1 P41146 1/20 0.33
ADRA2B P18089 1/20 0.33
ADRA2C P18825 1/20 0.33
SLC6A2 P23975 1/20 0.33
HTR2A P28223 1/20 0.33
SLC6A4 P31645 1/20 0.33
ADRA1A P35348 1/20 0.33
OPRK1 P41145 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL8003015 0.86 TSHR (0.35) TSHRALDH1A1AOC3LMNAOPRM1
SCHEMBL8496529 0.84 TSHR (0.45) TSHRALDH1A1AOC3NR1H2NR1H3
Hydrochloric Acid SCHEMBL9172317 0.83 TSHR (0.44) TSHRALDH1A1AOC3NR1H2NR1H3
Bromide SCHEMBL9169395 0.83 TSHR (0.44) TSHRALDH1A1AOC3NR1H2NR1H3
Hydrochloric Acid SCHEMBL11410885 0.82 TSHR (0.43) TSHRALDH1A1NR1H2NR1H3LMNA
SCHEMBL8887364 0.80 TSHR (0.41) TSHRALDH1A1NR1H2NR1H3LMNA
SCHEMBL8887363 0.78 TSHR (0.39) TSHRALDH1A1NR1H2NR1H3LMNA
Sulfuric Acid SCHEMBL9170625 0.78 TSHR (0.39) TSHRALDH1A1NR1H2NR1H3LMNA
Hydrochloric Acid SCHEMBL11782079 0.74
SCHEMBL8987977 0.71

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0109838-A2 Light and heat-sensitive recording material FUJI PHOTO FILM CO., LTD. (JP) 1984-05-30 EP disclosed