Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.52 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.47 |
| ▸ | RECQL | P46063 | 1/20 | 0.47 |
| ▸ | KCNA3 | P22001 | 1/20 | 0.47 |
| ▸ | PPARA | Q07869 | 2/20 | 0.46 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.46 |
| ▸ | LTA4H | P09960 | 2/20 | 0.46 |
| ▸ | PLA2G2A | P14555 | 1/20 | 0.46 |
| ▸ | HTR1B | P28222 | 2/20 | 0.43 |
| ▸ | HTR1D | P28221 | 1/20 | 0.43 |
| ▸ | FDPS | P14324 | 3/20 | 0.42 |
| ▸ | PARP10 | Q53GL7 | 1/20 | 0.42 |
| ▸ | MTNR1A | P48039 | 1/20 | 0.41 |
| ▸ | MTNR1B | P49286 | 1/20 | 0.41 |
| ▸ | PKM | P14618 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8095513 | 0.81 | KCNA3 (0.54) | TAAR1ALDH1A1RECQLKCNA3PPARA | |
| SCHEMBL1754085 | 0.77 | KCNA3 (0.58) | TAAR1ALDH1A1RECQLKCNA3PPARA | |
| SCHEMBL4332540 | 0.74 | PPARA (0.56) | TAAR1ALDH1A1RECQLKCNA3PPARA | |
| SCHEMBL4332538 | 0.74 | PPARA (0.56) | TAAR1ALDH1A1RECQLKCNA3PPARA | |
| SCHEMBL21414831 | 0.73 | KCNA3 (0.54) | TAAR1ALDH1A1RECQLKCNA3PPARA | |
| SCHEMBL9715083 | 0.73 | KCNA3 (0.54) | TAAR1ALDH1A1RECQLKCNA3PPARA | |
| SCHEMBL11052425 | 0.73 | KCNA3 (0.54) | TAAR1ALDH1A1RECQLKCNA3PPARA | |
| SCHEMBL82056 | 0.73 | PPARA (0.73) | ALDH1A1RECQLKCNA3PPARAMTNR1A | |
| SCHEMBL22710207 | 0.72 | KCNA3 (0.52) | TAAR1ALDH1A1RECQLKCNA3PPARA | |
| SCHEMBL10264550 | 0.72 | KCNA3 (0.52) | TAAR1ALDH1A1RECQLKCNA3PPARA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4456616-A | 7-Oxabicycloheptane substituted amino prostaglandin analogs and their use in inhibiting platelet aggregation and bronchoconstriction | E. R. SQUIBB & SONS, INC. (US) | 1984-06-26 | — | — | US | disclosed |