Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KCNA3 | P22001 | 1/20 | 0.58 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.52 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.52 |
| ▸ | RECQL | P46063 | 1/20 | 0.52 |
| ▸ | HTR1B | P28222 | 2/20 | 0.52 |
| ▸ | HTR1D | P28221 | 1/20 | 0.52 |
| ▸ | LTA4H | P09960 | 3/20 | 0.50 |
| ▸ | PPARA | Q07869 | 1/20 | 0.50 |
| ▸ | CHRNB2 | P17787 | 2/20 | 0.48 |
| ▸ | CHRNB4 | P30926 | 2/20 | 0.48 |
| ▸ | CHRNA3 | P32297 | 2/20 | 0.48 |
| ▸ | CHRNA7 | P36544 | 2/20 | 0.48 |
| ▸ | CHRNA4 | P43681 | 2/20 | 0.48 |
| ▸ | PKM | P14618 | 1/20 | 0.47 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.47 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.47 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.47 |
| ▸ | HDAC7 | Q8WUI4 | 1/20 | 0.47 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.47 |
| ▸ | HDAC10 | Q969S8 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10202896 | 0.89 | KCNA3 (0.62) | KCNA3TAAR1ALDH1A1RECQLHTR1B | |
| SCHEMBL14524692 | 0.88 | SMN1; SMN2 (0.47) | KCNA3ALDH1A1LTA4HPPARAHDAC6 | |
| SCHEMBL6562705 | 0.88 | LSS (0.56) | LTA4HCHRNB2CHRNB4CHRNA3CHRNA7 | |
| SCHEMBL13301359 | 0.88 | LSS (0.56) | LTA4HCHRNB2CHRNB4CHRNA3CHRNA7 | |
| SCHEMBL22147343 | 0.87 | KCNA3 (0.67) | KCNA3TAAR1ALDH1A1RECQLHTR1B | |
| SCHEMBL5099859 | 0.84 | MAPK1 (0.46) | CHRNB2CHRNA4 | |
| SCHEMBL12958141 | 0.83 | KDM4E (0.52) | ALDH1A1HTR1BHTR1DLTA4HPPARA | |
| SCHEMBL12958258 | 0.83 | LTA4H (0.53) | LTA4HHDAC1HDAC2 | |
| SCHEMBL2601695 | 0.83 | PPARA (0.42) | KCNA3TAAR1ALDH1A1RECQLHTR1B | |
| SCHEMBL21414831 | 0.83 | KCNA3 (0.54) | KCNA3TAAR1ALDH1A1RECQLHTR1B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 132 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-116670108-A | Ether compounds as volatiles for treating amino acid based substrates such as skin and hair | 迈图高新材料有限责任公司 | 2023-08-29 | — | — | CN | claimed |
| CN-116670108-A | Ether compounds as volatiles for treating amino acid based substrates such as skin and hair | 迈图高新材料有限责任公司 | 2023-08-29 | — | — | CN | disclosed |
| US-20230041563-A1 | N-(1,3,4-OXADIAZOL-2-YL)ARYLCARBOXAMIDES OR SALTS THEREOF, PREPARATION METHODS, HERBICIDAL COMPOSITIONS AND USES THEREOF | QINGDAO KINGAGROOT CHEMICAL COMPOUND CO., LTD. (CN) | 2023-02-09 | — | — | US | disclosed |
| CN-114981243-A | 6-membered heteroarylaminosulfonamides for treating diseases and conditions mediated by deficiency of CFTR activity | 健赞公司 | 2022-08-30 | — | — | CN | disclosed |
| US-11332440-B2 | 4-oxo-alkylated tetramic acid compound, and preparation method thereof | BEIJING JOEKAI BIOTECH. LLC (CN) | 2022-05-17 | — | — | US | disclosed |
| US-20220018826-A1 | COLORIMETRIC PLASMONIC NANOSENSOR FOR DOSIMETRY OF THERAPEUTIC LEVELS OF IONIZING RADIATION | ARIZONA BOARD OF REGENTS ON BEHALF OF ARIZONA STATE UNIVERSITY (US) | 2022-01-20 | — | — | US | disclosed |
| US-11130733-B2 | 4-OXO-alkylated tetramic acid compound, preparation method and use thereof | BEIJING JOEKAI BIOTECH. LLC (CN) | 2021-09-28 | — | — | US | disclosed |
| US-20210186970-A1 | SELECTIVE CALCIUM CHANNEL ANTAGONISTS | NORTHWESTERN UNIVERSITY | 2021-06-24 | — | — | US | disclosed |
| US-10941134-B2 | AMPK-activating heterocyclic compounds and methods for using the same | RIGEL PHARMACEUTICALS, INC. (US) | 2021-03-09 | — | — | US | disclosed |
| US-20200361868-A1 | 4-OXO-ALKYLATED TETRAMIC ACID COMPOUND, PREPARATION METHOD AND USE THEREOF | BEIJING JOEKAI BIOTECH. LLC (CN) | 2020-11-19 | — | — | US | disclosed |
| US-20070203183-A1 | Diaryl piperidines as CB1 modulators | SCHERING CORPORATION | 2007-08-30 | — | — | US | disclosed |
| US-20070203183-A1 | Diaryl piperidines as CB1 modulators | SCHERING CORPORATION | 2007-08-30 | — | — | US | disclosed |
| US-20070179150-A1 | NITROSATED PROTON PUMP INHIBITORS, COMPOSITIONS AND METHODS OF USE | NITROMED, INC. (US) | 2007-08-02 | — | — | US | disclosed |
| US-7211590-B2 | Nitrosated proton pump inhibitors, compositions and methods of use | NITROMED, INC. (US) | 2007-05-01 | — | — | US | disclosed |
| US-20070037821-A1 | Nitrosated glutamic acid compounds, compositions and methods of use | NITROMED, INC. (US) | 2007-02-15 | — | — | US | disclosed |
| US-20070032484-A1 | Cathepsin K inhibitors | ROCHE PALO ALTO LLC | 2007-02-08 | — | — | US | disclosed |
| US-7163958-B2 | Nitrosated nonsteroidal antiinflammatory compounds, compositions and methods of use | NITROMED INC. (US) | 2007-01-16 | — | — | US | disclosed |
| US-20070010571-A1 | Nitrosated and nitrosylated cardiovascular compounds, compositions and methods of use | NITROMED, INC. (US) | 2007-01-11 | — | — | US | disclosed |
| EP-1727824-A1 | PROCESS FOR THE PREPARATION OF CLARITHROMYCIN | Sandoz AG (CH) | 2006-12-06 | — | — | EP | disclosed |
| WO-2005090377-A1 | PROCESS FOR THE PREPARATION OF CLARITHROMYCIN | SANDOZ AG (CH) | 2005-09-29 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (11 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-11130733-B2 | 4-OXO-alkylated tetramic acid compound, preparation method and use thereof | HTT, PARK7, PSEN1 | KCNA3 928/4885TAAR1 105/4885ALDH1A1 1056/4885 |
| US-11332440-B2 | 4-oxo-alkylated tetramic acid compound, and preparation method thereof | PSEN1, PSEN2, APP | KCNA3 1253/4885TAAR1 172/4885ALDH1A1 747/4885 |
| US-20070203183-A1 | Diaryl piperidines as CB1 modulators | CNR1, CNR2, GPR119 | KCNA3 1579/4885TAAR1 42/4885ALDH1A1 1216/4885 |
| US-20070032484-A1 | Cathepsin K inhibitors | CTSK, CTSS, CTSF | KCNA3 1057/4885TAAR1 2307/4885ALDH1A1 1616/4885 |
| US-20230041563-A1 | N-(1,3,4-OXADIAZOL-2-YL)ARYLCARBOXAMIDES OR SALTS THEREOF, PREPARATION METHODS, HERBICIDAL COMPOSITIONS AND USES THEREOF | CYP2B6, CBR3, CYP2A6 | KCNA3 521/4885TAAR1 1200/4885ALDH1A1 2826/4885 |
| US-20070179150-A1 | NITROSATED PROTON PUMP INHIBITORS, COMPOSITIONS AND METHODS OF USE | NOS1, PTGS1, NOS2 | KCNA3 3463/4885TAAR1 3035/4885ALDH1A1 1299/4885 |
| US-20070010571-A1 | Nitrosated and nitrosylated cardiovascular compounds, compositions and methods of use | REN, ACE, AGTR1 | KCNA3 2515/4885TAAR1 452/4885ALDH1A1 312/4885 |
| US-20200361868-A1 | 4-OXO-ALKYLATED TETRAMIC ACID COMPOUND, PREPARATION METHOD AND USE THEREOF | HTT, PARK7, PSEN1 | KCNA3 928/4885TAAR1 105/4885ALDH1A1 1056/4885 |
| US-10941134-B2 | AMPK-activating heterocyclic compounds and methods for using the same | PRKAG1, PRKAG2, PRKAB1 | KCNA3 3581/4885TAAR1 4045/4885ALDH1A1 807/4885 |
| US-20210186970-A1 | SELECTIVE CALCIUM CHANNEL ANTAGONISTS | CACNA1C, CACNA1B, CACNA1G | KCNA3 66/4885TAAR1 1963/4885ALDH1A1 3916/4885 |
| US-20070037821-A1 | Nitrosated glutamic acid compounds, compositions and methods of use | GLS, NOS2, NOS1 | KCNA3 3965/4885TAAR1 1918/4885ALDH1A1 883/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.