SCHEMBL11111485

SCHEMBL11111485

CC1CC(C)N(CCN)C1

nearest known ligand 0.32

Predicted protein targets (top 2)

geneUniProtsupporting neighboursconfidence
SIGMAR1 Q99720 1/20 0.32
MAPT P10636 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL10845848 0.87 SIGMAR1 (0.38) SIGMAR1
SCHEMBL3921394 0.83
SCHEMBL20723859 0.80 SIGMAR1 (0.41) SIGMAR1
SCHEMBL18912886 0.80 SIGMAR1 (0.41) SIGMAR1
SCHEMBL26972431 0.79
SCHEMBL10900221 0.77 AGL (0.36) SIGMAR1MAPT
SCHEMBL15363045 0.74 SIGMAR1 (0.41) SIGMAR1
SCHEMBL19529321 0.73
SCHEMBL17040385 0.73
SCHEMBL19577858 0.72

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0021592-A1 Phenylsulphonamide derivatives, a process for their preparation and their use as medicines BEECHAM - WUELFING GmbH & Co. KG (DE) 1981-01-07 EP claimed
EP-0021580-A1 Sulphonamide derivatives, a process for their preparation and their use as medicines BEECHAM - WUELFING GmbH & Co. KG (DE) 1981-01-07 EP claimed
US-4436908-A ANTIARRHYTHMIA AGENTS Wuelfing, Johann A. (DE) 1984-03-13 US disclosed
EP-0021580-B1 SULPHONAMIDE DERIVATIVES, A PROCESS FOR THEIR PREPARATION AND THEIR USE AS MEDICINES BEECHAM - WUELFING GmbH & Co. KG (DE) 1983-12-14 EP disclosed
US-4372955-A Anti-arrythmic sulphonamide compositions Wuelfing, Johann A. (DE) 1983-02-08 US disclosed
EP-0021580-A1 Sulphonamide derivatives, a process for their preparation and their use as medicines BEECHAM - WUELFING GmbH & Co. KG (DE) 1981-01-07 EP disclosed