Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP2C9 | P11712 | 1/20 | 0.39 |
| ▸ | MAPT | P10636 | 4/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.38 |
| ▸ | LMNA | P02545 | 1/20 | 0.38 |
| ▸ | ESR2 | Q92731 | 2/20 | 0.35 |
| ▸ | MEN1 | O00255 | 2/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.35 |
| ▸ | DGAT1 | O75907 | 2/20 | 0.35 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.35 |
| ▸ | GAA | P10253 | 1/20 | 0.35 |
| ▸ | SPHK1 | Q9NYA1 | 5/20 | 0.34 |
| ▸ | SOAT1 | P35610 | 1/20 | 0.34 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.33 |
| ▸ | CYP2C8 | P10632 | 1/20 | 0.33 |
| ▸ | S1PR3 | Q99500 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11111534 | 1.00 | CYP2C9 (0.39) | CYP2C9MAPTALDH1A1LMNAESR2 | |
| SCHEMBL10944220 | 0.93 | SPHK1 (0.34) | CYP2C9MAPTALDH1A1LMNAMEN1 | |
| SCHEMBL10944228 | 0.93 | SPHK1 (0.34) | CYP2C9MAPTALDH1A1LMNAMEN1 | |
| SCHEMBL11108266 | 0.93 | CYP2C9 (0.39) | CYP2C9MAPTALDH1A1LMNAMEN1 | |
| SCHEMBL11108270 | 0.93 | CYP2C9 (0.39) | CYP2C9MAPTALDH1A1LMNAMEN1 | |
| SCHEMBL10948432 | 0.91 | SPHK1 (0.37) | CYP2C9MAPTALDH1A1LMNADGAT1 | |
| SCHEMBL10948427 | 0.91 | SPHK1 (0.37) | CYP2C9MAPTALDH1A1LMNADGAT1 | |
| SCHEMBL7672341 | 0.85 | CYP2C9 (0.37) | CYP2C9MAPTALDH1A1LMNAESR2 | |
| SCHEMBL7672347 | 0.85 | CYP2C9 (0.37) | CYP2C9MAPTALDH1A1LMNAESR2 | |
| SCHEMBL11110515 | 0.83 | TSHR (0.41) | CYP2C9MAPTALDH1A1LMNAMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0064193-B1 | 4,4'-BIS-(CYCLOHEXYL)-BIPHENYL DERIVATIVES THAT CONTAIN FLUORINE, DIELECTRICS CONTAINING THEM, AND ELECTRO-OPTICAL INDICATOR ELEMENT | MERCK PATENT GmbH (DE) | 1984-07-25 | — | — | EP | disclosed |
| US-4419264-A | Fluorine-containing 4,4'-bis-(cyclohexyl)-biphenyl derivatives, and dielectrics and electro-optical display elements containing them | MERCK PATENT GESELLSCHAFT MIT BESCHRANKTER HAFTUNG (DE) | 1983-12-06 | — | — | US | disclosed |
| EP-0064193-A1 | 4,4'-Bis-(cyclohexyl)-biphenyl derivatives that contain fluorine, dielectrics containing them, and electro-optical indicator element | MERCK PATENT GmbH (DE) | 1982-11-10 | — | — | EP | disclosed |