Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.64 |
| ▸ | HPGD | P15428 | 2/20 | 0.64 |
| ▸ | MAPT | P10636 | 2/20 | 0.58 |
| ▸ | POLB | P06746 | 2/20 | 0.57 |
| ▸ | APEX1 | P27695 | 2/20 | 0.57 |
| ▸ | RECQL | P46063 | 1/20 | 0.57 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.56 |
| ▸ | TSHR | P16473 | 2/20 | 0.56 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.56 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.56 |
| ▸ | ALOX5 | P09917 | 5/20 | 0.53 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.53 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.52 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.52 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.52 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.52 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.52 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.52 |
| ▸ | MEN1 | O00255 | 2/20 | 0.52 |
| ▸ | NPC1 | O15118 | 1/20 | 0.52 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10821618 | 0.83 | APEX1 (0.62) | ALDH1A1HPGDMAPTPOLBAPEX1 | |
| SCHEMBL9175427 | 0.81 | SMN1; SMN2 (0.56) | ALDH1A1HPGDMAPTPOLBAPEX1 | |
| SCHEMBL9174275 | 0.81 | ALDH1A1 (0.55) | ALDH1A1HPGDMAPTPOLBAPEX1 | |
| SCHEMBL9443121 | 0.81 | ALDH1A1 (0.61) | ALDH1A1HPGDMAPTPOLBAPEX1 | |
| SCHEMBL29023738 | 0.80 | MAPT (0.66) | ALDH1A1HPGDMAPTPOLBAPEX1 | |
| SCHEMBL9175312 | 0.80 | ALDH1A1 (0.54) | ALDH1A1HPGDMAPTPOLBAPEX1 | |
| SCHEMBL10358412 | 0.80 | ALDH1A1 (0.60) | ALDH1A1HPGDMAPTPOLBAPEX1 | |
| SCHEMBL10037466 | 0.79 | APEX1 (0.64) | ALDH1A1HPGDMAPTPOLBAPEX1 | |
| SCHEMBL10643298 | 0.79 | APEX1 (0.61) | ALDH1A1HPGDMAPTPOLBAPEX1 | |
| SCHEMBL10989220 | 0.79 | CYP1A2 (0.67) | ALDH1A1HPGDMAPTPOLBAPEX1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0126030-A2 | Process for the preparation of beta-(benzothiazolylthio) and beta-(benzimidazolylthio) carboxylic acids | CIBA-GEIGY AG (CH) | 1984-11-21 | — | — | EP | disclosed |