Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 3/20 | 0.44 |
| ▸ | THRB | P10828 | 2/20 | 0.44 |
| ▸ | CES2 | O00748 | 4/20 | 0.38 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.38 |
| ▸ | CTSL | P07711 | 1/20 | 0.38 |
| ▸ | CTSB | P07858 | 1/20 | 0.38 |
| ▸ | GMNN | O75496 | 1/20 | 0.38 |
| ▸ | TP53 | P04637 | 1/20 | 0.38 |
| ▸ | POLB | P06746 | 1/20 | 0.38 |
| ▸ | MAPT | P10636 | 1/20 | 0.38 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.38 |
| ▸ | BLM | P54132 | 1/20 | 0.38 |
| ▸ | CA2 | P00918 | 1/20 | 0.37 |
| ▸ | DNM1 | Q05193 | 6/20 | 0.36 |
| ▸ | CES1 | P23141 | 3/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.35 |
| ▸ | LMNA | P02545 | 2/20 | 0.35 |
| ▸ | MEN1 | O00255 | 1/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29569167 | 1.00 | TSHR (0.44) | TSHRTHRBCES2HSD17B10CTSL | |
| SCHEMBL18558301 | 0.88 | — | — | |
| SCHEMBL5034231 | 0.84 | THRB (0.40) | TSHRTHRBCES2HSD17B10CTSL | |
| SCHEMBL17396992 | 0.84 | THRB (0.40) | TSHRTHRBCES2HSD17B10CTSL | |
| SCHEMBL31516168 | 0.84 | THRB (0.40) | TSHRTHRBCES2HSD17B10CTSL | |
| SCHEMBL1221777 | 0.82 | TSHR (0.57) | TSHRTHRBCES2HSD17B10CTSL | |
| SCHEMBL867481 | 0.82 | TSHR (0.57) | TSHRTHRBCES2HSD17B10CTSL | |
| SCHEMBL1220054 | 0.82 | TSHR (0.57) | TSHRTHRBCES2HSD17B10CTSL | |
| SCHEMBL20634256 | 0.82 | TSHR (0.57) | TSHRTHRBCES2HSD17B10CTSL | |
| SCHEMBL9329131 | 0.82 | TSHR (0.57) | TSHRTHRBCES2HSD17B10CTSL |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0108149-A1 | PROCESS FOR PREPARING DIALKYL TRISULFIDES | PENNWALT CORPORATION (US) | 1984-05-16 | — | — | EP | disclosed |