Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAOB | P27338 | 16/20 | 0.71 |
| ▸ | MAOA | P21397 | 4/20 | 0.60 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.58 |
| ▸ | HPGD | P15428 | 3/20 | 0.58 |
| ▸ | NPC1 | O15118 | 2/20 | 0.58 |
| ▸ | RAB9A | P51151 | 2/20 | 0.58 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.58 |
| ▸ | GRM5 | P41594 | 1/20 | 0.58 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.58 |
| ▸ | RELA | Q04206 | 1/20 | 0.58 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.58 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.58 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.57 |
| ▸ | LMNA | P02545 | 1/20 | 0.57 |
| ▸ | GAA | P10253 | 1/20 | 0.57 |
| ▸ | MAPT | P10636 | 1/20 | 0.53 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL619838 | 0.98 | MAOB (0.71) | MAOBMAOAALDH1A1HPGDNPC1 | |
| SCHEMBL13339685 | 0.90 | MAOB (0.67) | MAOBMAOAALDH1A1HPGDNPC1 | |
| Hydrochloric Acid SCHEMBL3493369 | 0.89 | MAOB (0.65) | MAOBMAOAALDH1A1HPGDNPC1 | |
| SCHEMBL4726898 | 0.83 | MAOB (1.00) | MAOBMAOAALDH1A1HPGDNPC1 | |
| SCHEMBL4348338 | 0.83 | KDM4E (0.60) | MAOBALDH1A1HPGDSMN1; SMN2KDM4E | |
| SCHEMBL3493811 | 0.81 | MAOB (0.58) | MAOBMAOAALDH1A1HPGDKDM4E | |
| SCHEMBL3493808 | 0.81 | MAOB (0.58) | MAOBMAOAALDH1A1HPGDKDM4E | |
| SCHEMBL618064 | 0.81 | MAOB (0.52) | MAOBMAOAALDH1A1HPGDNPC1 | |
| SCHEMBL13339743 | 0.81 | ALDH1A1 (0.56) | MAOBMAOAALDH1A1HPGDNPC1 | |
| SCHEMBL618063 | 0.81 | MAOB (0.52) | MAOBMAOAALDH1A1HPGDNPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4479007-A | Chroman-4-ones and process for preparing same | BAYER AKTIENGESELLSCHAFT (DE) | 1984-10-23 | — | — | US | disclosed |
| US-4415741-A | REACTING O-HYDROXYACETOPHENONE AND CYCLOPENTANONE | BAYER AKTIENGESELLSCHAFT (DE) | 1983-11-15 | — | — | US | disclosed |
| US-4185112-A | INSECTICIDES, MITICIDES | BAYER AKTIENGESELLSCHAFT (DE) | 1980-01-22 | — | — | US | disclosed |