Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DNTT | P04053 | 1/20 | 0.43 |
| ▸ | TRPA1 | O75762 | 4/20 | 0.40 |
| ▸ | NR4A2 | P43354 | 2/20 | 0.40 |
| ▸ | NFKB1 | P19838 | 3/20 | 0.39 |
| ▸ | NFKB2 | Q00653 | 3/20 | 0.39 |
| ▸ | RELA | Q04206 | 3/20 | 0.39 |
| ▸ | MEN1 | O00255 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.36 |
| ▸ | LMNA | P02545 | 1/20 | 0.36 |
| ▸ | POLB | P06746 | 1/20 | 0.36 |
| ▸ | HPGD | P15428 | 1/20 | 0.36 |
| ▸ | NR4A1 | P22736 | 1/20 | 0.36 |
| ▸ | PTPN7 | P35236 | 1/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.36 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.36 |
| ▸ | PPARG | P37231 | 2/20 | 0.35 |
| ▸ | PPARD | Q03181 | 1/20 | 0.35 |
| ▸ | PPARA | Q07869 | 1/20 | 0.35 |
| ▸ | MAPT | P10636 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11112565 | 0.78 | DNTT (0.48) | DNTTTRPA1NR4A2NFKB1NFKB2 | |
| SCHEMBL11861471 | 0.74 | TRPA1 (0.43) | DNTTTRPA1NR4A2ALDH1A1KMT2A | |
| SCHEMBL10619340 | 0.74 | DNTT (0.43) | DNTTTRPA1NR4A2NFKB1NFKB2 | |
| SCHEMBL11867800 | 0.71 | DNTT (0.42) | DNTTTRPA1NR4A2MEN1ALDH1A1 | |
| SCHEMBL10704086 | 0.71 | DNTT (0.44) | DNTTTRPA1NR4A2PPARGPPARD | |
| SCHEMBL17451520 | 0.71 | PPARG (0.67) | DNTTTRPA1NR4A2MEN1ALDH1A1 | |
| SCHEMBL15287190 | 0.71 | PPARG (0.67) | DNTTTRPA1NR4A2MEN1ALDH1A1 | |
| SCHEMBL11800847 | 0.71 | PPARG (0.67) | DNTTTRPA1NR4A2MEN1ALDH1A1 | |
| SCHEMBL10621637 | 0.70 | DNTT (0.43) | DNTTTRPA1NR4A2NFKB1NFKB2 | |
| SCHEMBL10631459 | 0.70 | PPARG (0.44) | DNTTTRPA1NR4A2NFKB1NFKB2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0106576-A2 | Novel 5-membered cyclic compounds, process for the production thereof, and pharmaceutical use thereof | TEIJIN LIMITED (JP) | 1984-04-25 | — | — | EP | disclosed |