Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HPGD | P15428 | 2/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.32 |
| ▸ | NPC1 | O15118 | 1/20 | 0.32 |
| ▸ | MAPT | P10636 | 1/20 | 0.32 |
| ▸ | RAB9A | P51151 | 1/20 | 0.32 |
| ▸ | LMNA | P02545 | 1/20 | 0.32 |
| ▸ | CYP27B1 | O15528 | 1/20 | 0.32 |
| ▸ | OGG1 | O15527 | 1/20 | 0.31 |
| ▸ | ACP1 | P24666 | 1/20 | 0.31 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.31 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.31 |
| ▸ | TSHR | P16473 | 1/20 | 0.31 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.31 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.30 |
| ▸ | GAA | P10253 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10925949 | 0.87 | TDP1 (0.40) | NPC1MAPTRAB9AOGG1ACP1 | |
| SCHEMBL10705611 | 0.82 | TDP1 (0.36) | NPC1RAB9AOGG1ACP1MAPK1 | |
| SCHEMBL11115393 | 0.82 | CBLB (0.33) | HPGDLMNACYP27B1MAPK1GAA | |
| SCHEMBL9662442 | 0.81 | TDP1 (0.37) | HPGDSMN1; SMN2NPC1MAPTRAB9A | |
| SCHEMBL11110979 | 0.80 | CYP27B1 (0.35) | SMN1; SMN2MAPTLMNACYP27B1MAPK1 | |
| SCHEMBL9663631 | 0.79 | TDP1 (0.35) | MAPTMAPK1CYP3A4TSHRTDP1 | |
| SCHEMBL9146314 | 0.78 | TDP1 (0.37) | SMN1; SMN2MAPTMAPK1CYP3A4TSHR | |
| SCHEMBL3804802 | 0.78 | TDP1 (0.37) | SMN1; SMN2MAPTMAPK1CYP3A4TSHR | |
| SCHEMBL10921864 | 0.78 | CYP3A4 (0.43) | MAPTLMNACYP27B1MAPK1CYP3A4 | |
| SCHEMBL11063181 | 0.76 | CYP3A4 (0.44) | HPGDMAPTLMNACYP3A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0115400-A1 | Triazole antifungal agents | Pfizer Limited (GB) | 1984-08-08 | — | — | EP | disclosed |