Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 4/20 | 0.46 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.42 |
| ▸ | IRAK4 | Q9NWZ3 | 1/20 | 0.38 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.38 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.38 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.38 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.38 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.38 |
| ▸ | TDP1 | Q9NUW8 | 3/20 | 0.38 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.38 |
| ▸ | MAOB | P27338 | 1/20 | 0.38 |
| ▸ | LMNA | P02545 | 1/20 | 0.37 |
| ▸ | GAA | P10253 | 1/20 | 0.37 |
| ▸ | MEN1 | O00255 | 1/20 | 0.37 |
| ▸ | GLO1 | Q04760 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11106971 | 0.90 | MAPT (0.46) | MAPTKDM4EIRAK4SMN1; SMN2ALDH1A1 | |
| SCHEMBL11107922 | 0.90 | MAPT (0.43) | MAPTKDM4ECYP1A2CYP3A4CYP2D6 | |
| SCHEMBL11108515 | 0.85 | CYP1A2 (0.42) | MAPTKDM4ECYP1A2CYP3A4CYP2D6 | |
| SCHEMBL11105073 | 0.84 | ALDH1A1 (0.40) | MAPTKDM4ECYP1A2CYP3A4CYP2C19 | |
| SCHEMBL11104931 | 0.83 | ALDH1A1 (0.48) | MAPTKDM4ECYP1A2CYP2C19ALDH1A1 | |
| SCHEMBL11104143 | 0.83 | ALDH1A1 (0.40) | MAPTCYP1A2CYP2C19ALDH1A1TDP1 | |
| SCHEMBL11102036 | 0.83 | MAPT (0.48) | MAPTKDM4ECYP1A2SMN1; SMN2ALDH1A1 | |
| SCHEMBL11106321 | 0.83 | ALDH1A1 (0.50) | MAPTCYP1A2CYP3A4CYP2D6CYP2C19 | |
| SCHEMBL11107250 | 0.82 | ALDH1A1 (0.50) | MAPTKDM4ESMN1; SMN2ALDH1A1TDP1 | |
| SCHEMBL11108113 | 0.80 | POLB (0.39) | MAPTCYP1A2CYP3A4CYP2D6CYP2C19 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4463001-A | ANTIULCER AGENTS | FARMITALIA CARLO ERBA S.P.A. (IT) | 1984-07-31 | — | — | US | disclosed |