Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 3/20 | 0.46 |
| ▸ | MEN1 | O00255 | 1/20 | 0.46 |
| ▸ | HPGD | P15428 | 1/20 | 0.44 |
| ▸ | POLB | P06746 | 3/20 | 0.43 |
| ▸ | NPC1 | O15118 | 3/20 | 0.43 |
| ▸ | RAB9A | P51151 | 3/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.42 |
| ▸ | TP53 | P04637 | 2/20 | 0.41 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.41 |
| ▸ | ATM | Q13315 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.40 |
| ▸ | GAA | P10253 | 3/20 | 0.40 |
| ▸ | MAPT | P10636 | 1/20 | 0.40 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.40 |
| ▸ | TSHR | P16473 | 1/20 | 0.40 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.39 |
| ▸ | HTT | P42858 | 1/20 | 0.39 |
| ▸ | CNR2 | P34972 | 1/20 | 0.39 |
| ▸ | NFE2L2 | Q16236 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11110232 | 0.85 | KMT2A (0.49) | KMT2AMEN1HPGDPOLBNPC1 | |
| SCHEMBL11105353 | 0.84 | CTSD (0.47) | KMT2AHPGDNPC1RAB9ASMN1; SMN2 | |
| SCHEMBL11111950 | 0.79 | CA1 (0.47) | KMT2AHPGDSMN1; SMN2TP53L3MBTL1 | |
| SCHEMBL16962927 | 0.77 | KMT2A (0.50) | KMT2AMEN1HPGDPOLBNPC1 | |
| SCHEMBL5617204 | 0.76 | HPGD (0.54) | KMT2AMEN1HPGDPOLBNPC1 | |
| SCHEMBL10723118 | 0.75 | KMT2A (0.45) | KMT2AMEN1HPGDPOLBNPC1 | |
| SCHEMBL10769623 | 0.75 | KMT2A (0.51) | KMT2AMEN1HPGDPOLBNPC1 | |
| SCHEMBL3863254 | 0.74 | KMT2A (0.58) | KMT2AMEN1HPGDPOLBNPC1 | |
| SCHEMBL16962238 | 0.72 | KMT2A (0.49) | KMT2AMEN1HPGDPOLBNPC1 | |
| Alcohol SCHEMBL27668805 | 0.72 | NPC1 (0.55) | KMT2AMEN1HPGDPOLBNPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4454158-A | Allyl amine MAO inhibitors | MERRELL TORAUDE ET COMPAGNIE (FR) | 1984-06-12 | — | — | US | disclosed |