Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FNTA | P49354 | 5/20 | 0.59 |
| ▸ | FNTB | P49356 | 5/20 | 0.59 |
| ▸ | LTA4H | P09960 | 1/20 | 0.49 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.48 |
| ▸ | CA2 | P00918 | 2/20 | 0.47 |
| ▸ | CA1 | P00915 | 1/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.46 |
| ▸ | USP2 | O75604 | 1/20 | 0.46 |
| ▸ | TP53 | P04637 | 1/20 | 0.46 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.46 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.46 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11106357 | 0.90 | FNTA (0.48) | FNTAFNTBCA2CA1ALDH1A1 | |
| SCHEMBL11108513 | 0.87 | PPID (0.50) | FNTAFNTBALDH1A1TP53 | |
| SCHEMBL2322946 | 0.84 | FNTA (0.61) | FNTAFNTBLTA4HNPSR1CA2 | |
| SCHEMBL11267806 | 0.83 | FOLH1 (0.48) | LTA4HNPSR1 | |
| SCHEMBL11285335 | 0.83 | MAPT (0.44) | FNTAFNTBCA2CA1ALDH1A1 | |
| SCHEMBL11278576 | 0.83 | FNTA (0.52) | FNTAFNTBCA2CA1ALDH1A1 | |
| SCHEMBL11111423 | 0.82 | FNTA (0.51) | FNTAFNTBLTA4HNPSR1ALDH1A1 | |
| SCHEMBL2333601 | 0.82 | FNTA (0.59) | FNTAFNTBLTA4HNPSR1CA2 | |
| SCHEMBL11274797 | 0.82 | ACE (0.61) | NPSR1 | |
| SCHEMBL11283051 | 0.81 | ALDH1A1 (0.46) | FNTAFNTBCA2CA1ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4460601-A | Dipeptides having a methionine residue and possessing a protective action for the liver | MAGGIONI FARMACEUTICI, S.P.A. (IT) | 1984-07-17 | — | — | US | claimed |
| US-4460601-A | Dipeptides having a methionine residue and possessing a protective action for the liver | MAGGIONI FARMACEUTICI, S.P.A. (IT) | 1984-07-17 | — | — | US | disclosed |
| US-4339600-A | ENZYME INHIBITORS | E. R. SQUIBB & SONS, INC. (US) | 1982-07-13 | — | — | US | disclosed |
| US-4199512-A | Compounds for alleviating hypertension | E. R. SQUIBB & SONS, INC. (US) | 1980-04-22 | — | — | US | disclosed |
| US-4173704-A | HYPOTENSIVE AGENTS | E. R. SQUIBB & SONS, INC. (US) | 1979-11-06 | — | — | US | disclosed |
| US-4140797-A | MERCAPTOACYL AMINO ACIDS, ENZYME INHIBITORS | E. R. SQUIBB & SONS, INC. (US) | 1979-02-20 | — | — | US | disclosed |
| US-4140786-A | ENZYME INHIBITORS | E. R. SQUIBB & SONS, INC. (US) | 1979-02-20 | — | — | US | disclosed |
| US-4112119-A | MERCAPTOACYL AMINOACIDS | E. R. SQUIBB & SONS, INC. (US) | 1978-09-05 | — | — | US | disclosed |
| US-4053651-A | MERCAPTOACYL AMINO ACIDS, ENZYME INHIBITORS | E. R. SQUIBB & SONS, INC. (US) | 1977-10-11 | — | — | US | disclosed |