Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.68 |
| ▸ | MAPT | P10636 | 3/20 | 0.68 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.51 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.51 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.51 |
| ▸ | HPGD | P15428 | 1/20 | 0.51 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.51 |
| ▸ | MEN1 | O00255 | 3/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.47 |
| ▸ | RAB9A | P51151 | 2/20 | 0.47 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.47 |
| ▸ | ICMT | O60725 | 3/20 | 0.42 |
| ▸ | RHOC | P08134 | 1/20 | 0.40 |
| ▸ | RHOA | P61586 | 1/20 | 0.40 |
| ▸ | DRD4 | P21917 | 1/20 | 0.39 |
| ▸ | LMNA | P02545 | 2/20 | 0.38 |
| ▸ | HTT | P42858 | 2/20 | 0.38 |
| ▸ | NPC1 | O15118 | 1/20 | 0.38 |
| ▸ | TP53 | P04637 | 1/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11114661 | 0.86 | MAPT (0.65) | ALDH1A1MAPTHPGDMEN1KMT2A | |
| SCHEMBL11113758 | 0.86 | ALDH1A1 (0.48) | ALDH1A1MAPTL3MBTL1CYP1A2CYP2C9 | |
| SCHEMBL2065279 | 0.82 | ALDH1A1 (1.00) | ALDH1A1MAPTL3MBTL1DRD4 | |
| Hydrochloric Acid SCHEMBL3634998 | 0.80 | ALDH1A1 (0.94) | ALDH1A1MAPTL3MBTL1DRD4 | |
| SCHEMBL11115361 | 0.79 | MAPT (0.54) | ALDH1A1MAPTCYP1A2CYP2C9CYP2C19 | |
| Hydrochloric Acid SCHEMBL29727944 | 0.78 | ALDH1A1 (0.90) | ALDH1A1MAPTL3MBTL1HPGDDRD4 | |
| SCHEMBL11112599 | 0.78 | MAPT (0.52) | ALDH1A1MAPTL3MBTL1CYP1A2CYP2C9 | |
| SCHEMBL4970157 | 0.78 | ALDH1A1 (0.89) | ALDH1A1MAPTL3MBTL1 | |
| SCHEMBL11526524 | 0.78 | ALDH1A1 (0.50) | ALDH1A1MAPTL3MBTL1CYP1A2CYP2C9 | |
| SCHEMBL11115302 | 0.77 | MAPT (0.52) | ALDH1A1MAPTCYP1A2CYP2C9CYP2C19 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0058868-B1 | DERIVATIVES OF TETRAHYDROPYRIMIDINON, PROCESS FOR THEIR PREPARATION AND HERBICIDES CONTAINING THOSE DERIVATIVES AS ACTIVE PRODUCTS | NIHON TOKUSHU NOYAKU SEIZO K.K. (JP) | 1984-04-11 | — | — | EP | disclosed |
| US-4402731-A | Herbicidally active novel substituted tetrahydropyrimidinones | NIHON TOKUSHU NOYAKU SEIZO K.K. (JP) | 1983-09-06 | — | — | US | disclosed |
| EP-0058868-A1 | Derivatives of tetrahydropyrimidinon, process for their preparation and herbicides containing those derivatives as active products | NIHON TOKUSHU NOYAKU SEIZO K.K. (JP) | 1982-09-01 | — | — | EP | disclosed |