Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.46 |
| ▸ | ATM | Q13315 | 2/20 | 0.44 |
| ▸ | HTT | P42858 | 1/20 | 0.44 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.37 |
| ▸ | ACACB | O00763 | 5/20 | 0.36 |
| ▸ | ADRA1D | P25100 | 1/20 | 0.34 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.34 |
| ▸ | ADRA1B | P35368 | 1/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.34 |
| ▸ | HPGD | P15428 | 2/20 | 0.34 |
| ▸ | TRPM8 | Q7Z2W7 | 1/20 | 0.34 |
| ▸ | PDE7A | Q13946 | 2/20 | 0.33 |
| ▸ | LMNA | P02545 | 1/20 | 0.33 |
| ▸ | GAA | P10253 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3708949 | 0.87 | HDAC3 (0.43) | KDM4EATMHTTSIGMAR1ACACB | |
| SCHEMBL16496561 | 0.82 | ACACB (0.45) | KDM4ESIGMAR1ACACBALDH1A1HPGD | |
| SCHEMBL20480150 | 0.80 | KDM4E (0.47) | KDM4EATMHTTSIGMAR1ACACB | |
| SCHEMBL30609093 | 0.78 | ALDH1A1 (0.46) | KDM4EHTTALDH1A1HPGDLMNA | |
| SCHEMBL11113320 | 0.77 | KDM4E (0.44) | KDM4EATMHTTSIGMAR1ACACB | |
| SCHEMBL20480419 | 0.77 | ACACB (0.54) | KDM4EATMHTTACACB | |
| SCHEMBL16335052 | 0.76 | KDM4E (0.50) | KDM4EATMHTTALDH1A1HPGD | |
| SCHEMBL16496996 | 0.76 | IDO1 (0.46) | KDM4EACACBALDH1A1HPGDTRPM8 | |
| SCHEMBL29624718 | 0.76 | IDO1 (0.46) | KDM4EACACBALDH1A1HPGDTRPM8 | |
| SCHEMBL11114131 | 0.73 | ATM (0.64) | KDM4EATMHTTSIGMAR1ADRA1D |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4479007-A | Chroman-4-ones and process for preparing same | BAYER AKTIENGESELLSCHAFT (DE) | 1984-10-23 | — | — | US | disclosed |
| US-4415741-A | REACTING O-HYDROXYACETOPHENONE AND CYCLOPENTANONE | BAYER AKTIENGESELLSCHAFT (DE) | 1983-11-15 | — | — | US | disclosed |
| US-4185112-A | INSECTICIDES, MITICIDES | BAYER AKTIENGESELLSCHAFT (DE) | 1980-01-22 | — | — | US | disclosed |