Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CDC7 | O00311 | 13/20 | 0.97 |
| ▸ | DBF4 | Q9UBU7 | 13/20 | 0.97 |
| ▸ | CCNE1 | P24864 | 3/20 | 0.62 |
| ▸ | CDK2 | P24941 | 3/20 | 0.62 |
| ▸ | TRPM8 | Q7Z2W7 | 2/20 | 0.53 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.50 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.49 |
| ▸ | GAA | P10253 | 1/20 | 0.49 |
| ▸ | RAB9A | P51151 | 1/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15048961 | 0.86 | CDC7 (0.73) | CDC7DBF4CCNE1CDK2TRPM8 | |
| SCHEMBL10958086 | 0.85 | CDC7 (1.00) | CDC7DBF4CCNE1CDK2 | |
| SCHEMBL15049359 | 0.81 | RAB9A (0.69) | CDC7DBF4TRPM8SMN1; SMN2KDM4E | |
| SCHEMBL15048913 | 0.81 | RAB9A (0.73) | CDC7DBF4TRPM8SMN1; SMN2KDM4E | |
| SCHEMBL15049252 | 0.81 | CDC7 (0.67) | CDC7DBF4TRPM8SMN1; SMN2KDM4E | |
| SCHEMBL3328924 | 0.81 | SMN1; SMN2 (0.76) | CDC7DBF4CCNE1CDK2SMN1; SMN2 | |
| SCHEMBL17374874 | 0.81 | CDC7 (0.68) | CDC7DBF4CCNE1CDK2TRPM8 | |
| SCHEMBL16113884 | 0.79 | CDC7 (1.00) | CDC7DBF4CCNE1CDK2SMN1; SMN2 | |
| SCHEMBL27996876 | 0.79 | CDC7 (0.63) | CDC7DBF4CCNE1CDK2TRPM8 | |
| SCHEMBL27996905 | 0.78 | CDC7 (0.61) | CDC7DBF4TRPM8SMN1; SMN2KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-104220069-A | Trpm8 antagonists | DOMPE SPA | 2014-12-17 | — | — | CN | claimed |
| CN-104220069-A | Trpm8 antagonists | DOMPE SPA | 2014-12-17 | — | — | CN | disclosed |
| EP-0097323-A2 | 2-(4-Pyridyl)-thiazole derivatives | SCHERING CORPORATION (US) | 1984-01-04 | — | — | EP | disclosed |