Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GAA | P10253 | 1/20 | 0.48 |
| ▸ | TSHR | P16473 | 3/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.42 |
| ▸ | CDK1 | P06493 | 1/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.37 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.37 |
| ▸ | NPC1 | O15118 | 1/20 | 0.37 |
| ▸ | THRB | P10828 | 1/20 | 0.36 |
| ▸ | RECQL | P46063 | 1/20 | 0.36 |
| ▸ | TP53 | P04637 | 1/20 | 0.36 |
| ▸ | GLA | P06280 | 1/20 | 0.36 |
| ▸ | MAPT | P10636 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11113146 | 0.94 | GAA (0.54) | GAACDK1ALDH1A1KDM4ENPC1 | |
| SCHEMBL10999615 | 0.94 | GAA (0.51) | GAATSHRSMN1; SMN2CDK1ALDH1A1 | |
| SCHEMBL11115042 | 0.93 | ALDH1A1 (0.43) | GAATSHRALDH1A1KDM4ENPC1 | |
| SCHEMBL10686494 | 0.89 | GAA (0.53) | GAATSHRSMN1; SMN2CDK1ALDH1A1 | |
| SCHEMBL11000316 | 0.88 | GAA (0.57) | GAATSHRCDK1ALDH1A1KDM4E | |
| SCHEMBL10916479 | 0.87 | GAA (0.52) | GAATSHRSMN1; SMN2CDK1ALDH1A1 | |
| SCHEMBL11004041 | 0.86 | TSHR (0.46) | GAATSHRALDH1A1KDM4ENPC1 | |
| SCHEMBL10455714 | 0.85 | GAA (0.53) | GAATSHRSMN1; SMN2CDK1THRB | |
| SCHEMBL11112932 | 0.85 | ALDH1A1 (0.41) | GAASMN1; SMN2ALDH1A1KDM4ENPC1 | |
| SCHEMBL10687516 | 0.83 | GAA (0.60) | GAACDK1ALDH1A1KDM4ENPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0023422-B1 | HERBICIDAL SULFONAMIDES, PREPARATION AND USE THEREOF, AND COMPOSITIONS CONTAINING THEM | E.I. DU PONT DE NEMOURS AND COMPANY (US) | 1984-02-22 | — | — | EP | claimed |