Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TLR8 | Q9NR97 | 5/20 | 0.46 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.44 |
| ▸ | ALOX5 | P09917 | 2/20 | 0.44 |
| ▸ | MEN1 | O00255 | 1/20 | 0.44 |
| ▸ | TP53 | P04637 | 1/20 | 0.44 |
| ▸ | MAPT | P10636 | 1/20 | 0.44 |
| ▸ | TYR | P14679 | 1/20 | 0.44 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.44 |
| ▸ | TSHR | P16473 | 1/20 | 0.44 |
| ▸ | HTT | P42858 | 1/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.44 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.44 |
| ▸ | PTGS2 | P35354 | 3/20 | 0.41 |
| ▸ | LIPG | Q9Y5X9 | 1/20 | 0.41 |
| ▸ | SKP2 | Q13309 | 1/20 | 0.41 |
| ▸ | HTR2A | P28223 | 2/20 | 0.41 |
| ▸ | GPR84 | Q9NQS5 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15486053 | 0.98 | ALOX5 (0.47) | TLR8CYP3A4ALOX5MEN1TP53 | |
| SCHEMBL841582 | 0.98 | ALOX5 (0.47) | TLR8CYP3A4ALOX5MEN1TP53 | |
| SCHEMBL5379561 | 0.93 | TLR8 (0.42) | TLR8CYP3A4ALOX5MEN1TP53 | |
| SCHEMBL833088 | 0.92 | SKP2 (0.47) | TLR8CYP3A4ALOX5MEN1TP53 | |
| SCHEMBL5386049 | 0.91 | ALOX5 (0.43) | TLR8CYP3A4ALOX5MEN1TP53 | |
| SCHEMBL14681822 | 0.88 | ALOX5 (0.47) | TLR8CYP3A4ALOX5MEN1TP53 | |
| SCHEMBL18428550 | 0.88 | ALOX5 (0.47) | TLR8CYP3A4ALOX5MEN1TP53 | |
| SCHEMBL840888 | 0.88 | ALOX5 (0.47) | TLR8CYP3A4ALOX5MEN1TP53 | |
| SCHEMBL29739851 | 0.88 | ALOX5 (0.47) | TLR8CYP3A4ALOX5MEN1TP53 | |
| SCHEMBL5379612 | 0.86 | SKP2 (0.42) | TLR8CYP3A4ALOX5MEN1TP53 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4482657-A | Silica-polymer mixtures | POLYSAR LIMITED (CA) | 1984-11-13 | — | — | US | disclosed |