Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 2/20 | 0.36 |
| ▸ | HTR2A | P28223 | 3/20 | 0.35 |
| ▸ | SLC6A4 | P31645 | 3/20 | 0.35 |
| ▸ | PPARA | Q07869 | 1/20 | 0.35 |
| ▸ | MRGPRX4 | Q96LA9 | 1/20 | 0.35 |
| ▸ | HSD11B1 | P28845 | 1/20 | 0.33 |
| ▸ | NPC1 | O15118 | 1/20 | 0.33 |
| ▸ | RAB9A | P51151 | 1/20 | 0.33 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.33 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.33 |
| ▸ | SLC1A5 | Q15758 | 1/20 | 0.32 |
| ▸ | TBXA2R | P21731 | 1/20 | 0.32 |
| ▸ | FNTA | P49354 | 1/20 | 0.32 |
| ▸ | FNTB | P49356 | 1/20 | 0.32 |
| ▸ | EZH2 | Q15910 | 2/20 | 0.32 |
| ▸ | MCL1 | Q07820 | 2/20 | 0.32 |
| ▸ | GPR119 | Q8TDV5 | 1/20 | 0.32 |
| ▸ | BCL2L1 | Q07817 | 1/20 | 0.31 |
| ▸ | VEGFA | P15692 | 1/20 | 0.31 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7979384 | 0.77 | MEN1 (0.41) | MAPTSLC6A4MRGPRX4HSD11B1EZH2 | |
| SCHEMBL6664928 | 0.71 | PPARA (0.42) | MAPTHTR2ASLC6A4PPARAMRGPRX4 | |
| SCHEMBL9099955 | 0.71 | PPARA (0.42) | MAPTHTR2ASLC6A4PPARAMRGPRX4 | |
| SCHEMBL11112179 | 0.70 | TDP1 (0.54) | MAPTPPARAFNTAFNTB | |
| SCHEMBL6062731 | 0.69 | TDP1 (0.62) | MAPTSLC6A4HSD11B1RAB9A | |
| SCHEMBL10769994 | 0.68 | MEN1 (0.45) | MAPTSLC6A4MRGPRX4HSD11B1SLC6A2 | |
| SCHEMBL9246156 | 0.67 | TDP1 (0.62) | SLC6A4HSD11B1 | |
| SCHEMBL11399618 | 0.67 | PPARA (0.40) | MAPTHTR2ASLC6A4PPARAMRGPRX4 | |
| SCHEMBL8680245 | 0.67 | TDP1 (0.51) | MAPTSLC6A4HSD11B1SLC6A2EZH2 | |
| SCHEMBL11556883 | 0.66 | TDP1 (0.42) | VEGFA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4459305-A | INSECTICIDE, MITICIDE | DAINIPPON SOCHUGIKU KABUSHIKI KAISHA (JP) | 1984-07-10 | — | — | US | disclosed |