Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TDP1 | Q9NUW8 | 4/20 | 0.51 |
| ▸ | LMNA | P02545 | 2/20 | 0.51 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.51 |
| ▸ | CNR1 | P21554 | 1/20 | 0.51 |
| ▸ | ATM | Q13315 | 1/20 | 0.51 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.51 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.43 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.36 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.36 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.36 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.36 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.36 |
| ▸ | MEN1 | O00255 | 2/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.36 |
| ▸ | TSHR | P16473 | 2/20 | 0.35 |
| ▸ | FFAR4 | Q5NUL3 | 1/20 | 0.33 |
| ▸ | SLC6A4 | P31645 | 2/20 | 0.32 |
| ▸ | HSD11B1 | P28845 | 1/20 | 0.32 |
| ▸ | MAPT | P10636 | 1/20 | 0.32 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6062731 | 0.91 | TDP1 (0.62) | TDP1LMNAADRA2ACNR1ATM | |
| SCHEMBL9246156 | 0.91 | TDP1 (0.62) | TDP1LMNAADRA2ACNR1ATM | |
| SCHEMBL11556883 | 0.82 | TDP1 (0.42) | TDP1LMNAADRA2ACNR1ATM | |
| SCHEMBL7979384 | 0.81 | MEN1 (0.41) | TDP1LMNAADRA2ACNR1ATM | |
| SCHEMBL8624463 | 0.79 | TDP1 (0.68) | TDP1LMNAADRA2ACNR1ATM | |
| SCHEMBL9862144 | 0.77 | TDP1 (0.82) | TDP1LMNAADRA2ACNR1ATM | |
| SCHEMBL9558539 | 0.77 | TDP1 (0.82) | TDP1LMNAADRA2ACNR1ATM | |
| SCHEMBL8304052 | 0.77 | TDP1 (0.82) | TDP1LMNAADRA2ACNR1ATM | |
| SCHEMBL7751255 | 0.77 | LMNA (0.65) | TDP1LMNAADRA2ACNR1ATM | |
| SCHEMBL9361346 | 0.76 | TDP1 (0.56) | TDP1LMNAADRA2ACNR1ATM |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1998016487-A1 | 1S TO 1R EPIMERIZATIONS OF PYRETHROID INTERMEDIATES | FMC CORPORATION (US) | 1998-04-23 | — | — | WO | disclosed |