Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 3/20 | 0.53 |
| ▸ | NPC1 | O15118 | 2/20 | 0.53 |
| ▸ | RAB9A | P51151 | 2/20 | 0.53 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.53 |
| ▸ | MEN1 | O00255 | 1/20 | 0.53 |
| ▸ | USP2 | O75604 | 1/20 | 0.53 |
| ▸ | BLM | P54132 | 1/20 | 0.53 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.53 |
| ▸ | PHLPP2 | Q6ZVD8 | 2/20 | 0.47 |
| ▸ | BRD4 | O60885 | 6/20 | 0.44 |
| ▸ | BRD3 | Q15059 | 4/20 | 0.44 |
| ▸ | BRD2 | P25440 | 1/20 | 0.44 |
| ▸ | BRDT | Q58F21 | 1/20 | 0.44 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.42 |
| ▸ | TP53 | P04637 | 2/20 | 0.42 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.42 |
| ▸ | TSHR | P16473 | 1/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.42 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.42 |
| ▸ | PKM | P14618 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11213651 | 1.00 | MAPT (0.53) | MAPTNPC1RAB9AKDM4EMEN1 | |
| SCHEMBL11505519 | 0.88 | CA2 (0.56) | MAPTNPC1RAB9AKDM4EMEN1 | |
| SCHEMBL11505518 | 0.88 | CA2 (0.56) | MAPTNPC1RAB9AKDM4EMEN1 | |
| SCHEMBL14004211 | 0.87 | RPS6KA3 (0.54) | MAPTNPC1RAB9AKDM4EMEN1 | |
| SCHEMBL6123730 | 0.87 | RPS6KA3 (0.54) | MAPTNPC1RAB9AKDM4EMEN1 | |
| SCHEMBL8375098 | 0.87 | MAPT (0.51) | MAPTNPC1RAB9AKDM4EMEN1 | |
| SCHEMBL8375096 | 0.87 | MAPT (0.51) | MAPTNPC1RAB9AKDM4EMEN1 | |
| SCHEMBL12758032 | 0.87 | RPS6KA3 (0.54) | MAPTNPC1RAB9AKDM4EMEN1 | |
| SCHEMBL8375101 | 0.85 | RPS6KA3 (0.52) | MAPTNPC1RAB9AKDM4EMEN1 | |
| SCHEMBL5353001 | 0.82 | MAPT (0.54) | MAPTNPC1RAB9AKDM4EMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0109624-A2 | Process for producing shaped articles made from polyurethane-polyurea which may be cellular | BASF Aktiengesellschaft (DE) | 1984-05-30 | — | — | EP | disclosed |
| US-4313872-A | MONDAZO AND DISAZO DYES | CASSELLA AKTIENGESELLSCHAFT (DE) | 1982-02-02 | — | — | US | disclosed |