Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.61 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.61 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.61 |
| ▸ | POLB | P06746 | 1/20 | 0.56 |
| ▸ | HSD17B3 | P37058 | 7/20 | 0.48 |
| ▸ | NOTUM | Q6P988 | 2/20 | 0.48 |
| ▸ | MEN1 | O00255 | 1/20 | 0.48 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.48 |
| ▸ | MAPT | P10636 | 1/20 | 0.44 |
| ▸ | NPC1 | O15118 | 1/20 | 0.44 |
| ▸ | MITF | O75030 | 1/20 | 0.44 |
| ▸ | RAB9A | P51151 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11111811 | 0.87 | KDM4E (0.47) | KDM4EL3MBTL1ALDH1A1POLBHSD17B3 | |
| SCHEMBL11548268 | 0.83 | KDM4E (0.67) | KDM4EL3MBTL1ALDH1A1POLBHSD17B3 | |
| SCHEMBL31182095 | 0.83 | KDM4E (0.67) | KDM4EL3MBTL1ALDH1A1POLBHSD17B3 | |
| SCHEMBL25784150 | 0.81 | KDM4E (0.66) | KDM4EL3MBTL1ALDH1A1POLBHSD17B3 | |
| SCHEMBL23875654 | 0.79 | HSD17B3 (0.68) | KDM4EL3MBTL1ALDH1A1POLBHSD17B3 | |
| SCHEMBL4806681 | 0.79 | KDM4E (0.68) | KDM4EL3MBTL1ALDH1A1POLBHSD17B3 | |
| SCHEMBL11108730 | 0.79 | HSD17B3 (0.66) | KDM4EL3MBTL1ALDH1A1POLBHSD17B3 | |
| SCHEMBL19224983 | 0.79 | HSD17B3 (0.66) | KDM4EL3MBTL1ALDH1A1POLBHSD17B3 | |
| SCHEMBL30982111 | 0.79 | HSD17B3 (0.68) | KDM4EL3MBTL1ALDH1A1POLBHSD17B3 | |
| SCHEMBL4809705 | 0.78 | KDM4E (0.63) | KDM4EL3MBTL1ALDH1A1POLBHSD17B3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0108715-A1 | Dibenzazepine carboxamides | CIBA-GEIGY AG (CH) | 1984-05-16 | — | — | EP | disclosed |