Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA12 | O43570 | 3/20 | 0.56 |
| ▸ | CA9 | Q16790 | 3/20 | 0.56 |
| ▸ | RECQL | P46063 | 1/20 | 0.54 |
| ▸ | TSHR | P16473 | 3/20 | 0.46 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.46 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.46 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.46 |
| ▸ | MEN1 | O00255 | 2/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.46 |
| ▸ | TP53 | P04637 | 1/20 | 0.46 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.44 |
| ▸ | BRD4 | O60885 | 3/20 | 0.43 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.41 |
| ▸ | HPGD | P15428 | 1/20 | 0.41 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.41 |
| ▸ | POLB | P06746 | 1/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.40 |
| ▸ | HTT | P42858 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11114762 | 0.94 | RECQL (0.62) | CA12CA9RECQLTSHRCYP1A2 | |
| SCHEMBL9462811 | 0.86 | CA12 (0.63) | CA12CA9RECQLTSHRCYP1A2 | |
| SCHEMBL5189488 | 0.83 | CA12 (0.60) | CA12CA9RECQLTSHRCYP1A2 | |
| SCHEMBL28318605 | 0.80 | RECQL (0.70) | CA12CA9RECQLTSHRCYP1A2 | |
| SCHEMBL11114456 | 0.78 | NSD2 (0.44) | CA12MEN1KMT2AALDH1A1BRD4 | |
| SCHEMBL11114752 | 0.78 | CYP1A2 (0.41) | CA12TSHRCYP1A2ALDH1A1L3MBTL1 | |
| SCHEMBL23716806 | 0.78 | RECQL (0.67) | CA12CA9RECQLTSHRCYP1A2 | |
| SCHEMBL635553 | 0.76 | CA12 (0.63) | CA12CA9RECQLTSHRCYP1A2 | |
| SCHEMBL9738480 | 0.76 | CA12 (0.63) | CA12CA9RECQLTSHRCYP1A2 | |
| SCHEMBL31391062 | 0.76 | CA12 (0.63) | CA12CA9RECQLTSHRCYP1A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4454135-A | ALSO MITICIDES | E. I. DU PONT DE NEMOURS AND COMPANY (US) | 1984-06-12 | — | — | US | claimed |
| US-4454135-A | ALSO MITICIDES | E. I. DU PONT DE NEMOURS AND COMPANY (US) | 1984-06-12 | — | — | US | disclosed |