SCHEMBL5189488

SCHEMBL5189488

CCCCNS(=O)(=O)c1ccccc1CCCC

nearest known ligand 0.60

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CA12 O43570 3/20 0.60
CA9 Q16790 3/20 0.60
RECQL P46063 1/20 0.57
TSHR P16473 3/20 0.49
CYP1A2 P05177 2/20 0.49
CYP3A4 P08684 2/20 0.49
CYP2C19 P33261 2/20 0.49
TDP1 Q9NUW8 2/20 0.49
MEN1 O00255 2/20 0.49
KMT2A Q03164 2/20 0.49
TP53 P04637 1/20 0.49
ALDH1A1 P00352 4/20 0.47
L3MBTL1 Q9Y468 1/20 0.44
KDM4E B2RXH2 2/20 0.43
HPGD P15428 1/20 0.43
HSD17B10 Q99714 1/20 0.43
ALOX12 P18054 1/20 0.43
POLB P06746 1/20 0.43
BRD4 O60885 1/20 0.42
SMN1; SMN2 Q16637 2/20 0.42

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL23716806 0.94 RECQL (0.67) CA12CA9RECQLTSHRCYP1A2
SCHEMBL9462811 0.90 CA12 (0.63) CA12CA9RECQLTSHRCYP1A2
SCHEMBL534942 0.84 RECQL (0.59) CA12CA9RECQLTSHRCYP1A2
SCHEMBL6612130 0.84 NSD2 (0.43) CA12CA9RECQLCYP3A4MEN1
SCHEMBL31367739 0.84 CA12 (0.51) CA12CA9RECQLTSHRCYP1A2
SCHEMBL28318605 0.84 RECQL (0.70) CA12CA9RECQLTSHRCYP1A2
SCHEMBL6193165 0.83 RECQL (0.42) CA12CA9RECQLCYP1A2CYP3A4
SCHEMBL11114464 0.83 CA12 (0.56) CA12CA9RECQLTSHRCYP1A2
SCHEMBL3068059 0.83 CA12 (0.51) CA12CA9RECQLTSHRCYP1A2
SCHEMBL226295 0.83 RECQL (0.52) CA12CA9RECQLTSHRCYP1A2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-7308912-B2 Laminate; an inner layer made of a low fuel permeability resin of polyphenylene sulfide, an outer layer of a low fuel permeability resin of an epoxy group-containing olefin polymer and an ethylene- alpha -olefin copolymer TOYODA GOSEI CO., LTD. (JP) 2007-12-18 US disclosed
EP-1582339-B1 Fuel tube TOYODA GOSEI KK (JP) 2007-09-05 EP disclosed
US-20050217745-A1 Fuel tube TOYODA GOSEI CO., LTD 2005-10-06 US disclosed
EP-1582339-A1 Fuel tube Toyoda Gosei Co., Ltd. (JP) 2005-10-05 EP disclosed