Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 3/20 | 0.56 |
| ▸ | RAB9A | P51151 | 3/20 | 0.56 |
| ▸ | MEN1 | O00255 | 2/20 | 0.56 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.56 |
| ▸ | NPC1 | O15118 | 2/20 | 0.56 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.56 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.56 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.56 |
| ▸ | PKM | P14618 | 1/20 | 0.48 |
| ▸ | HTT | P42858 | 1/20 | 0.48 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.42 |
| ▸ | CA12 | O43570 | 1/20 | 0.41 |
| ▸ | CA2 | P00918 | 1/20 | 0.41 |
| ▸ | CA9 | Q16790 | 1/20 | 0.41 |
| ▸ | TSHR | P16473 | 2/20 | 0.39 |
| ▸ | GFER | P55789 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.39 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.39 |
| ▸ | PTGS1 | P23219 | 3/20 | 0.39 |
| ▸ | PTGS2 | P35354 | 3/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11210086 | 1.00 | MAPT (0.56) | MAPTRAB9AMEN1KMT2ANPC1 | |
| SCHEMBL18270227 | 0.89 | PTGS1 (0.45) | MAPTMEN1KMT2AEPHX1TSHR | |
| SCHEMBL2406779 | 0.87 | TSHR (0.50) | TDP1EPHX1TSHRGFERALDH1A1 | |
| SCHEMBL25565017 | 0.84 | PTGS1 (0.47) | EPHX1TSHRPTGS1PTGS2LMNA | |
| SCHEMBL18211430 | 0.82 | ALDH1A1 (0.50) | MAPTRAB9AMEN1KMT2ANPC1 | |
| SCHEMBL25567556 | 0.82 | PLAU (0.44) | EPHX1TSHRALDH1A1PTGS1PTGS2 | |
| SCHEMBL18211412 | 0.82 | NPC1 (0.42) | MAPTRAB9ANPC1TDP1SMN1; SMN2 | |
| Cyanide SCHEMBL27500241 | 0.81 | EPHX1 (0.46) | TDP1EPHX1TSHRGFERALDH1A1 | |
| SCHEMBL11832834 | 0.81 | CYP3A4 (0.50) | MAPTMEN1KMT2ATDP1EPHX1 | |
| SCHEMBL9611208 | 0.76 | MAPT (0.70) | MAPTRAB9AMEN1KMT2ANPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0109624-A2 | Process for producing shaped articles made from polyurethane-polyurea which may be cellular | BASF Aktiengesellschaft (DE) | 1984-05-30 | — | — | EP | disclosed |
| US-4313872-A | MONDAZO AND DISAZO DYES | CASSELLA AKTIENGESELLSCHAFT (DE) | 1982-02-02 | — | — | US | disclosed |