Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 1/20 | 0.76 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.76 |
| ▸ | HPGD | P15428 | 1/20 | 0.74 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.68 |
| ▸ | POLB | P06746 | 1/20 | 0.60 |
| ▸ | LIPE | Q05469 | 6/20 | 0.56 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.56 |
| ▸ | MAPT | P10636 | 2/20 | 0.56 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.51 |
| ▸ | LMNA | P02545 | 1/20 | 0.50 |
| ▸ | HCRTR1 | O43613 | 1/20 | 0.46 |
| ▸ | HCRTR2 | O43614 | 1/20 | 0.46 |
| ▸ | THRB | P10828 | 1/20 | 0.46 |
| ▸ | MAPK8 | P45983 | 1/20 | 0.46 |
| ▸ | MAPK10 | P53779 | 1/20 | 0.46 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.45 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.45 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.45 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10495486 | 0.83 | KMT2A (0.70) | TSHRSMN1; SMN2HPGDKMT2APOLB | |
| SCHEMBL17440373 | 0.83 | KMT2A (0.70) | TSHRSMN1; SMN2HPGDKMT2APOLB | |
| SCHEMBL30435803 | 0.81 | KMT2A (0.68) | TSHRSMN1; SMN2HPGDKMT2APOLB | |
| SCHEMBL11337376 | 0.81 | HPGD (0.69) | TSHRSMN1; SMN2HPGDKMT2APOLB | |
| SCHEMBL11001462 | 0.81 | KMT2A (0.68) | TSHRSMN1; SMN2HPGDKMT2APOLB | |
| SCHEMBL13506000 | 0.80 | HPGD (0.71) | TSHRSMN1; SMN2HPGDKMT2APOLB | |
| SCHEMBL30980818 | 0.79 | TSHR (0.63) | TSHRSMN1; SMN2HPGDKMT2APOLB | |
| SCHEMBL706407 | 0.79 | TSHR (0.63) | TSHRSMN1; SMN2HPGDKMT2APOLB | |
| SCHEMBL6631292 | 0.79 | KMT2A (0.64) | TSHRSMN1; SMN2HPGDKMT2APOLB | |
| SCHEMBL3458686 | 0.78 | SMN1; SMN2 (0.55) | TSHRSMN1; SMN2HPGDKMT2APOLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0107866-A2 | Trihalomethylpyridine compounds | IMPERIAL CHEMICAL INDUSTRIES PLC (GB) | 1984-05-09 | — | — | EP | disclosed |
| EP-0028870-A1 | Phenoxypyridine compound | IMPERIAL CHEMICAL INDUSTRIES PLC (GB) | 1981-05-20 | — | — | EP | disclosed |
| EP-0021453-A2 | 2-Chloro-5-trichloromethylpyridine | IMPERIAL CHEMICAL INDUSTRIES PLC (GB) | 1981-01-07 | — | — | EP | disclosed |