Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 2/20 | 0.70 |
| ▸ | HPGD | P15428 | 1/20 | 0.67 |
| ▸ | POLB | P06746 | 1/20 | 0.62 |
| ▸ | TSHR | P16473 | 1/20 | 0.60 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.60 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.57 |
| ▸ | MAPT | P10636 | 2/20 | 0.57 |
| ▸ | LIPE | Q05469 | 6/20 | 0.49 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.49 |
| ▸ | THRB | P10828 | 1/20 | 0.47 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.46 |
| ▸ | LMNA | P02545 | 1/20 | 0.45 |
| ▸ | MEN1 | O00255 | 1/20 | 0.43 |
| ▸ | RAB9A | P51151 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13439671 | 0.89 | HPGD (0.58) | KMT2AHPGDPOLBTSHRSMN1; SMN2 | |
| SCHEMBL17440373 | 0.84 | KMT2A (0.70) | KMT2AHPGDPOLBTSHRSMN1; SMN2 | |
| SCHEMBL11001462 | 0.83 | KMT2A (0.68) | KMT2AHPGDPOLBTSHRSMN1; SMN2 | |
| SCHEMBL30435803 | 0.83 | KMT2A (0.68) | KMT2AHPGDPOLBTSHRSMN1; SMN2 | |
| SCHEMBL11114747 | 0.83 | TSHR (0.76) | KMT2AHPGDPOLBTSHRSMN1; SMN2 | |
| SCHEMBL3159767 | 0.83 | KMT2A (0.65) | KMT2AHPGDPOLBTSHRSMN1; SMN2 | |
| SCHEMBL11337376 | 0.83 | HPGD (0.69) | KMT2AHPGDPOLBTSHRSMN1; SMN2 | |
| SCHEMBL30997483 | 0.79 | KMT2A (0.63) | KMT2AHPGDPOLBTSHRSMN1; SMN2 | |
| SCHEMBL10495590 | 0.79 | L3MBTL1 (0.54) | KMT2AHPGDPOLBTSHRSMN1; SMN2 | |
| SCHEMBL13462727 | 0.79 | HPGD (0.53) | KMT2AHPGDPOLBTSHRSMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4863924-A | N-benzoyl urea compounds, antitumorous compositions containing them | ISHIHARA SANGYO KAISHA LTD. (JP) | 1989-09-05 | — | — | US | disclosed |
| EP-0226104-A2 | N-Benzoyl urea compounds, antitumorous compositions containing them, and process for their preparation | ISHIHARA SANGYO KAISHA, LTD. (JP) | 1987-06-24 | — | — | EP | disclosed |