Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.65 |
| ▸ | MAPT | P10636 | 6/20 | 0.65 |
| ▸ | KDM4E | B2RXH2 | 6/20 | 0.65 |
| ▸ | TSHR | P16473 | 3/20 | 0.65 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.65 |
| ▸ | HPGD | P15428 | 3/20 | 0.65 |
| ▸ | GAA | P10253 | 3/20 | 0.65 |
| ▸ | CA12 | O43570 | 2/20 | 0.61 |
| ▸ | CA4 | P22748 | 2/20 | 0.61 |
| ▸ | CA7 | P43166 | 2/20 | 0.61 |
| ▸ | CA9 | Q16790 | 2/20 | 0.61 |
| ▸ | CA14 | Q9ULX7 | 2/20 | 0.61 |
| ▸ | CA3 | P07451 | 1/20 | 0.61 |
| ▸ | CA6 | P23280 | 1/20 | 0.61 |
| ▸ | CA5A | P35218 | 1/20 | 0.61 |
| ▸ | CA5B | Q9Y2D0 | 1/20 | 0.61 |
| ▸ | RECQL | P46063 | 3/20 | 0.59 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.56 |
| ▸ | TP53 | P04637 | 1/20 | 0.56 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.56 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10454908 | 0.91 | ALDH1A1 (0.76) | ALDH1A1MAPTKDM4ETSHRHSD17B10 | |
| Hydrochloric Acid SCHEMBL9850546 | 0.86 | ALDH1A1 (0.60) | ALDH1A1MAPTKDM4ETSHRHSD17B10 | |
| SCHEMBL11283741 | 0.82 | CA12 (0.77) | ALDH1A1MAPTKDM4ETSHRHSD17B10 | |
| SCHEMBL11113504 | 0.82 | ALDH1A1 (0.52) | ALDH1A1MAPTKDM4ETSHRHSD17B10 | |
| Hydrochloric Acid SCHEMBL4443499 | 0.81 | ALDH1A1 (0.78) | ALDH1A1MAPTKDM4ETSHRHSD17B10 | |
| SCHEMBL1493188 | 0.80 | ALDH1A1 (0.67) | ALDH1A1MAPTKDM4ETSHRHSD17B10 | |
| SCHEMBL731902 | 0.80 | ALDH1A1 (0.67) | ALDH1A1MAPTKDM4ETSHRHSD17B10 | |
| SCHEMBL1493191 | 0.80 | CA12 (0.79) | ALDH1A1MAPTKDM4ETSHRHSD17B10 | |
| SCHEMBL11111574 | 0.80 | ALDH1A1 (0.90) | ALDH1A1MAPTKDM4ETSHRHSD17B10 | |
| SCHEMBL1926256 | 0.80 | ALDH1A1 (0.67) | ALDH1A1MAPTKDM4ETSHRHSD17B10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0058868-B1 | DERIVATIVES OF TETRAHYDROPYRIMIDINON, PROCESS FOR THEIR PREPARATION AND HERBICIDES CONTAINING THOSE DERIVATIVES AS ACTIVE PRODUCTS | NIHON TOKUSHU NOYAKU SEIZO K.K. (JP) | 1984-04-11 | — | — | EP | disclosed |
| US-4402731-A | Herbicidally active novel substituted tetrahydropyrimidinones | NIHON TOKUSHU NOYAKU SEIZO K.K. (JP) | 1983-09-06 | — | — | US | disclosed |
| EP-0058868-A1 | Derivatives of tetrahydropyrimidinon, process for their preparation and herbicides containing those derivatives as active products | NIHON TOKUSHU NOYAKU SEIZO K.K. (JP) | 1982-09-01 | — | — | EP | disclosed |