Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 2/20 | 0.43 |
| ▸ | FAAH | O00519 | 2/20 | 0.40 |
| ▸ | TRPV1 | Q8NER1 | 2/20 | 0.40 |
| ▸ | TBXA2R | P21731 | 1/20 | 0.34 |
| ▸ | EPHX1 | P07099 | 2/20 | 0.34 |
| ▸ | GBA1 | P04062 | 2/20 | 0.33 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.33 |
| ▸ | GBA3 | Q9H227 | 1/20 | 0.33 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.33 |
| ▸ | S1PR2 | O95136 | 1/20 | 0.31 |
| ▸ | S1PR4 | O95977 | 1/20 | 0.31 |
| ▸ | S1PR1 | P21453 | 1/20 | 0.31 |
| ▸ | S1PR3 | Q99500 | 1/20 | 0.31 |
| ▸ | S1PR5 | Q9H228 | 1/20 | 0.31 |
| ▸ | ADH1C | P00326 | 1/20 | 0.31 |
| ▸ | ADH1A | P07327 | 1/20 | 0.31 |
| ▸ | ADH4 | P08319 | 1/20 | 0.31 |
| ▸ | CES2 | O00748 | 1/20 | 0.30 |
| ▸ | GMNN | O75496 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11115818 | 0.87 | TSHR (0.32) | TSHRMAPT | |
| SCHEMBL679389 | 0.86 | TSHR (0.59) | TSHRFAAHTRPV1EPHX1ALOX5 | |
| SCHEMBL11114883 | 0.79 | TSHR (0.35) | TSHRFAAHTRPV1ALOX5 | |
| SCHEMBL13396442 | 0.76 | TSHR (0.50) | TSHRFAAHTRPV1CYP1A2ALDH1A1 | |
| SCHEMBL20589931 | 0.75 | TSHR (0.61) | TSHRFAAHTRPV1EPHX1ALDH1A1 | |
| SCHEMBL29385123 | 0.75 | EPHX1 (0.48) | TSHREPHX1GBA1ALOX5CYP1A2 | |
| SCHEMBL28380195 | 0.75 | EPHX1 (0.48) | TSHREPHX1GBA1ALOX5CYP1A2 | |
| SCHEMBL29559353 | 0.75 | EPHX1 (0.48) | TSHREPHX1GBA1ALOX5CYP1A2 | |
| SCHEMBL28249807 | 0.75 | EPHX1 (0.48) | TSHREPHX1GBA1ALOX5CYP1A2 | |
| SCHEMBL11120561 | 0.74 | TSHR (0.41) | TSHRFAAHTRPV1EPHX1ALOX5 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0112633-A2 | Novel 5-thiaprostaglandin, process for production thereof, and pharmaceutical use thereof | TEIJIN LIMITED (JP) | 1984-07-04 | — | — | EP | claimed |
| EP-0112633-A2 | Novel 5-thiaprostaglandin, process for production thereof, and pharmaceutical use thereof | TEIJIN LIMITED (JP) | 1984-07-04 | — | — | EP | disclosed |