Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FFAR3 | O14843 | 3/20 | 0.37 |
| ▸ | HDAC3 | O15379 | 3/20 | 0.37 |
| ▸ | HDAC1 | Q13547 | 3/20 | 0.37 |
| ▸ | HDAC2 | Q92769 | 3/20 | 0.37 |
| ▸ | HDAC8 | Q9BY41 | 3/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.34 |
| ▸ | CES2 | O00748 | 1/20 | 0.33 |
| ▸ | CES1 | P23141 | 1/20 | 0.33 |
| ▸ | PPARA | Q07869 | 3/20 | 0.32 |
| ▸ | PPARG | P37231 | 2/20 | 0.32 |
| ▸ | HCAR2 | Q8TDS4 | 1/20 | 0.31 |
| ▸ | TSHR | P16473 | 1/20 | 0.31 |
| ▸ | RXRA | P19793 | 1/20 | 0.31 |
| ▸ | RXRB | P28702 | 1/20 | 0.31 |
| ▸ | RXRG | P48443 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11114851 | 1.00 | FFAR3 (0.37) | FFAR3HDAC3HDAC1HDAC2HDAC8 | |
| SCHEMBL5801512 | 0.85 | PPARG (0.33) | FFAR3ALDH1A1PPARAPPARGHCAR2 | |
| SCHEMBL5801514 | 0.85 | PPARG (0.33) | FFAR3ALDH1A1PPARAPPARGHCAR2 | |
| SCHEMBL5312074 | 0.82 | PPARG (0.31) | ALDH1A1PPARAPPARGHCAR2RXRA | |
| SCHEMBL5315515 | 0.82 | PPARG (0.31) | ALDH1A1PPARAPPARGHCAR2RXRA | |
| SCHEMBL5312077 | 0.82 | PPARG (0.31) | ALDH1A1PPARAPPARGHCAR2RXRA | |
| SCHEMBL11115380 | 0.80 | AKR1B1 (0.40) | ALDH1A1CES2CES1PPARAPPARG | |
| SCHEMBL11115383 | 0.80 | AKR1B1 (0.40) | ALDH1A1CES2CES1PPARAPPARG | |
| SCHEMBL11035705 | 0.79 | GPR84 (0.47) | ALDH1A1CES2CES1PPARAPPARG | |
| SCHEMBL11035712 | 0.79 | GPR84 (0.47) | ALDH1A1CES2CES1PPARAPPARG |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0052819-B1 | PROCESS FOR PREPARING AMIDINECARBOXYLIC ACIDS | UBE INDUSTRIES, LTD. (JP) | 1984-02-29 | — | — | EP | claimed |