Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 3/20 | 0.51 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.51 |
| ▸ | POLB | P06746 | 2/20 | 0.51 |
| ▸ | MAPT | P10636 | 2/20 | 0.51 |
| ▸ | DDX3X | O00571 | 1/20 | 0.51 |
| ▸ | HTT | P42858 | 1/20 | 0.51 |
| ▸ | CTDSP1 | Q9GZU7 | 1/20 | 0.51 |
| ▸ | TSHR | P16473 | 2/20 | 0.50 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.49 |
| ▸ | LMNA | P02545 | 1/20 | 0.48 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.47 |
| ▸ | HPGD | P15428 | 1/20 | 0.47 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.47 |
| ▸ | BLM | P54132 | 1/20 | 0.47 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11164763 | 0.86 | ALDH1A1 (0.56) | MEN1KMT2APOLBMAPTDDX3X | |
| SCHEMBL11158043 | 0.85 | ALDH1A1 (0.60) | MEN1KMT2APOLBMAPTDDX3X | |
| SCHEMBL2010242 | 0.84 | MAPT (0.56) | MEN1KMT2APOLBMAPTDDX3X | |
| SCHEMBL11115027 | 0.84 | ALDH1A1 (0.57) | MEN1KMT2APOLBMAPTDDX3X | |
| SCHEMBL4611265 | 0.83 | ALDH1A1 (0.52) | MEN1KMT2APOLBMAPTDDX3X | |
| SCHEMBL11291923 | 0.83 | MEN1 (0.50) | MEN1KMT2APOLBMAPTDDX3X | |
| SCHEMBL16943226 | 0.82 | MAPT (0.56) | MEN1KMT2APOLBMAPTDDX3X | |
| SCHEMBL5605034 | 0.82 | ALDH1A1 (0.51) | MEN1KMT2APOLBMAPTDDX3X | |
| SCHEMBL6231289 | 0.82 | MAPT (0.53) | MEN1KMT2APOLBMAPTDDX3X | |
| SCHEMBL3476083 | 0.82 | ALDH1A1 (0.51) | MEN1KMT2APOLBMAPTDDX3X |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0058868-B1 | DERIVATIVES OF TETRAHYDROPYRIMIDINON, PROCESS FOR THEIR PREPARATION AND HERBICIDES CONTAINING THOSE DERIVATIVES AS ACTIVE PRODUCTS | NIHON TOKUSHU NOYAKU SEIZO K.K. (JP) | 1984-04-11 | — | — | EP | disclosed |
| US-4402731-A | Herbicidally active novel substituted tetrahydropyrimidinones | NIHON TOKUSHU NOYAKU SEIZO K.K. (JP) | 1983-09-06 | — | — | US | disclosed |