Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | P2RX4 | Q99571 | 4/20 | 0.57 |
| ▸ | LMNA | P02545 | 1/20 | 0.56 |
| ▸ | TSHR | P16473 | 1/20 | 0.56 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.56 |
| ▸ | SCN4A | P35499 | 1/20 | 0.56 |
| ▸ | SCN5A | Q14524 | 1/20 | 0.56 |
| ▸ | SCN9A | Q15858 | 1/20 | 0.56 |
| ▸ | BCHE | P06276 | 3/20 | 0.38 |
| ▸ | ACHE | P22303 | 3/20 | 0.38 |
| ▸ | HSD17B3 | P37058 | 1/20 | 0.37 |
| ▸ | MYC | P01106 | 1/20 | 0.37 |
| ▸ | PARP1 | P09874 | 1/20 | 0.36 |
| ▸ | NOTUM | Q6P988 | 1/20 | 0.36 |
| ▸ | HTR1A | P08908 | 1/20 | 0.36 |
| ▸ | HTR2A | P28223 | 1/20 | 0.36 |
| ▸ | HTR7 | P34969 | 1/20 | 0.36 |
| ▸ | HTR6 | P50406 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.35 |
| ▸ | HPGD | P15428 | 1/20 | 0.35 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11116245 | 0.92 | LMNA (0.72) | P2RX4LMNATSHRMAPK1SCN4A | |
| SCHEMBL11111792 | 0.78 | P2RX4 (0.57) | P2RX4LMNATSHRMAPK1SCN4A | |
| SCHEMBL11114782 | 0.76 | NOTUM (0.53) | SCN9AHSD17B3NOTUMHTR2A | |
| Carbamazepine SCHEMBL29433237 | 0.72 | LMNA (1.00) | P2RX4LMNATSHRMAPK1SCN4A | |
| Carbamazepine SCHEMBL29360181 | 0.72 | LMNA (1.00) | P2RX4LMNATSHRMAPK1SCN4A | |
| Carbamazepine SCHEMBL21639 | 0.72 | LMNA (1.00) | P2RX4LMNATSHRMAPK1SCN4A | |
| Carbamazepine SCHEMBL6477112 | 0.72 | LMNA (1.00) | P2RX4LMNATSHRMAPK1SCN4A | |
| Carbamazepine SCHEMBL31685158 | 0.72 | LMNA (1.00) | P2RX4LMNATSHRMAPK1SCN4A | |
| SCHEMBL19263427 | 0.71 | LMNA (0.72) | P2RX4LMNATSHRMAPK1SCN4A | |
| Carbamazepine SCHEMBL5382102 | 0.71 | LMNA (0.96) | P2RX4LMNATSHRMAPK1SCN4A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0108715-A1 | Dibenzazepine carboxamides | CIBA-GEIGY AG (CH) | 1984-05-16 | — | — | EP | disclosed |