Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADORA1 | P30542 | 4/20 | 0.39 |
| ▸ | ADORA3 | P0DMS8 | 3/20 | 0.39 |
| ▸ | ADORA2A | P29274 | 2/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.35 |
| ▸ | DDAH1 | O94760 | 1/20 | 0.34 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.34 |
| ▸ | POLB | P06746 | 2/20 | 0.34 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.33 |
| ▸ | GLA | P06280 | 1/20 | 0.33 |
| ▸ | SMPD3 | Q9NY59 | 1/20 | 0.33 |
| ▸ | GAA | P10253 | 1/20 | 0.32 |
| ▸ | HTT | P42858 | 1/20 | 0.32 |
| ▸ | TP53 | P04637 | 1/20 | 0.32 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.32 |
| ▸ | ALK | Q9UM73 | 1/20 | 0.31 |
| ▸ | PDK2 | Q15119 | 1/20 | 0.31 |
| ▸ | PDK4 | Q16654 | 1/20 | 0.31 |
| ▸ | ATM | Q13315 | 1/20 | 0.31 |
| ▸ | TNKS2 | Q9H2K2 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3701645 | 0.89 | GLA (0.39) | ADORA1ADORA3ADORA2AKMT2AKDM4E | |
| SCHEMBL3708487 | 0.84 | ADORA1 (0.43) | ADORA1ADORA3ADORA2AKMT2ADDAH1 | |
| SCHEMBL443983 | 0.82 | ADORA1 (0.41) | ADORA1ADORA3ADORA2AKMT2ADDAH1 | |
| SCHEMBL18824951 | 0.80 | ADORA1 (0.34) | ADORA1ADORA3ADORA2AKMT2ADDAH1 | |
| SCHEMBL28285520 | 0.78 | ADORA1 (0.39) | ADORA1ADORA3ADORA2ADDAH1KDM4E | |
| SCHEMBL28285467 | 0.78 | ADORA1 (0.39) | ADORA1ADORA3ADORA2ADDAH1KDM4E | |
| SCHEMBL5851856 | 0.77 | SMPD3 (0.34) | ADORA1ADORA3ADORA2AKDM4EPOLB | |
| SCHEMBL11307460 | 0.75 | GLA (0.35) | ADORA1ADORA3ADORA2AKMT2AKDM4E | |
| SCHEMBL13384268 | 0.75 | ADORA1 (0.36) | ADORA1ADORA3ADORA2AKMT2ADDAH1 | |
| SCHEMBL6440203 | 0.75 | ADORA1 (0.33) | ADORA1ADORA3ADORA2AKMT2ADDAH1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0126531-A2 | 4,4'-Methylene-bis-(2-ethyl-5-methyl imidazole) and methods of producing and using the same | SHIKOKU CHEMICALS CORPORATION (JP) | 1984-11-28 | — | — | EP | disclosed |