Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.55 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.55 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.55 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.41 |
| ▸ | MEN1 | O00255 | 1/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.41 |
| ▸ | ACHE | P22303 | 1/20 | 0.37 |
| ▸ | TSHR | P16473 | 2/20 | 0.36 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.35 |
| ▸ | TP53 | P04637 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11583774 | 0.90 | ALDH1A1 (0.53) | ALDH1A1CYP3A4HSD17B10TDP1MEN1 | |
| SCHEMBL3817924 | 0.85 | TSHR (0.48) | ALDH1A1CYP3A4HSD17B10TDP1ACHE | |
| SCHEMBL11439117 | 0.82 | ALDH1A1 (0.49) | ALDH1A1CYP3A4HSD17B10TDP1MEN1 | |
| SCHEMBL11439122 | 0.82 | ALDH1A1 (0.49) | ALDH1A1CYP3A4HSD17B10TDP1MEN1 | |
| SCHEMBL1202631 | 0.82 | ALDH1A1 (0.47) | ALDH1A1CYP3A4HSD17B10TDP1MEN1 | |
| SCHEMBL8200128 | 0.82 | ALDH1A1 (0.38) | ALDH1A1CYP3A4HSD17B10TDP1MEN1 | |
| Demeton S SCHEMBL117918 | 0.79 | ALDH1A1 (0.59) | ALDH1A1CYP3A4HSD17B10TDP1MEN1 | |
| Demeton S SCHEMBL6732303 | 0.79 | ALDH1A1 (0.59) | ALDH1A1CYP3A4HSD17B10TDP1MEN1 | |
| Ethion SCHEMBL6047155 | 0.79 | ALDH1A1 (0.68) | ALDH1A1CYP3A4HSD17B10TDP1MEN1 | |
| SCHEMBL29389496 | 0.78 | ALDH1A1 (0.57) | ALDH1A1CYP3A4HSD17B10TDP1MEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0017738-B1 | AN INSECTICIDAL AND MITICIDAL COMPOSITION WHICH CONTAINS A CARBAMATE AND AN ORGANIC PHOSPHORUS COMPOUND, AND A METHOD OF CONTROLLING INSECTS AND MITES THEREWITH | IMPERIAL CHEMICAL INDUSTRIES PLC (GB) | 1984-08-08 | — | — | EP | claimed |
| EP-0017738-A1 | An insecticidal and miticidal composition which contains a carbamate and an organic phosphorus compound, and a method of controlling insects and mites therewith | IMPERIAL CHEMICAL INDUSTRIES PLC (GB) | 1980-10-29 | — | — | EP | claimed |
| EP-0017738-A1 | An insecticidal and miticidal composition which contains a carbamate and an organic phosphorus compound, and a method of controlling insects and mites therewith | IMPERIAL CHEMICAL INDUSTRIES PLC (GB) | 1980-10-29 | — | — | EP | disclosed |