Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | POLB | P06746 | 1/20 | 0.50 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.47 |
| ▸ | CNR1 | P21554 | 1/20 | 0.46 |
| ▸ | METAP2 | P50579 | 1/20 | 0.46 |
| ▸ | SIRT5 | Q9NXA8 | 1/20 | 0.46 |
| ▸ | TRPV1 | Q8NER1 | 1/20 | 0.45 |
| ▸ | UTS2R | Q9UKP6 | 1/20 | 0.45 |
| ▸ | CA12 | O43570 | 2/20 | 0.44 |
| ▸ | CA2 | P00918 | 2/20 | 0.44 |
| ▸ | CA9 | Q16790 | 2/20 | 0.44 |
| ▸ | CA1 | P00915 | 1/20 | 0.44 |
| ▸ | CA4 | P22748 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4984423 | 0.84 | POLB (0.63) | POLBEPHX1CNR1CA12CA2 | |
| SCHEMBL5558741 | 0.80 | CA12 (0.52) | CA12CA2CA1 | |
| SCHEMBL16728218 | 0.76 | ALDH1A1 (0.63) | CNR1SIRT5CA12CA2CA9 | |
| SCHEMBL4987592 | 0.75 | POLB (0.60) | POLB | |
| SCHEMBL27812203 | 0.75 | POLB (0.56) | POLBCNR1 | |
| SCHEMBL4985404 | 0.75 | SMN1; SMN2 (0.56) | POLBCNR1 | |
| SCHEMBL159191 | 0.74 | HSD17B10 (0.55) | — | |
| SCHEMBL30863856 | 0.74 | HSD17B10 (0.55) | — | |
| SCHEMBL2829819 | 0.74 | HSD17B10 (0.55) | — | |
| SCHEMBL31215092 | 0.74 | HSD17B10 (0.55) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0122155-A2 | Improvements in or relating to naphthylglycyl cephalosporin derivatives | ELI LILLY AND COMPANY (US) | 1984-10-17 | — | — | EP | disclosed |