Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTGS1 | P23219 | 1/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.47 |
| ▸ | HSD17B10 | Q99714 | 5/20 | 0.47 |
| ▸ | TDP1 | Q9NUW8 | 4/20 | 0.47 |
| ▸ | MAPT | P10636 | 4/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.47 |
| ▸ | CYP3A4 | P08684 | 3/20 | 0.47 |
| ▸ | HPGD | P15428 | 3/20 | 0.47 |
| ▸ | SLC15A2 | Q16348 | 3/20 | 0.47 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.47 |
| ▸ | BLM | P54132 | 1/20 | 0.47 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.47 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.47 |
| ▸ | HTR2B | P41595 | 1/20 | 0.47 |
| ▸ | ELANE | P08246 | 3/20 | 0.45 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.43 |
| ▸ | MEN1 | O00255 | 2/20 | 0.43 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.43 |
| ▸ | NR1I2 | O75469 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11084610 | 0.90 | PTGS1 (0.44) | PTGS1ALDH1A1HSD17B10TDP1MAPT | |
| SCHEMBL11081310 | 0.87 | ALDH1A1 (0.49) | PTGS1ALDH1A1HSD17B10TDP1MAPT | |
| SCHEMBL11078754 | 0.86 | PTGS1 (0.44) | PTGS1ALDH1A1HSD17B10TDP1MAPT | |
| SCHEMBL11078633 | 0.85 | KMT2A (0.67) | PTGS1ALDH1A1HSD17B10TDP1MAPT | |
| SCHEMBL11078627 | 0.85 | KMT2A (0.67) | PTGS1ALDH1A1HSD17B10TDP1MAPT | |
| SCHEMBL11079376 | 0.81 | ALDH1A1 (0.44) | PTGS1ALDH1A1HSD17B10TDP1MAPT | |
| SCHEMBL11176945 | 0.79 | PLCG1 (0.46) | PTGS1ALDH1A1HSD17B10TDP1MAPT | |
| SCHEMBL11176949 | 0.79 | PLCG1 (0.46) | PTGS1ALDH1A1HSD17B10TDP1MAPT | |
| SCHEMBL11116290 | 0.79 | ELANE (0.40) | PTGS1ALDH1A1HSD17B10TDP1MAPT | |
| SCHEMBL11077945 | 0.79 | PLCG1 (0.57) | PTGS1ALDH1A1HSD17B10TDP1MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4429128-A | CARBAPENICILLINS, THIENAMYCINS, BACTERICIDES | PFIZER INC. (US) | 1984-01-31 | — | — | US | disclosed |
| US-4348264-A | Photocatalyzed process for producing carbapenams and carbapen-2-ems | PFIZER INC. (US) | 1982-09-07 | — | — | US | disclosed |
| EP-0040494-A1 | Carbapenams and carbapen-2-ems and process therefor | PFIZER INC. (US) | 1981-11-25 | — | — | EP | disclosed |