SCHEMBL11116329

SCHEMBL11116329

CSCC(N)C(=O)N1CCCC1

nearest known ligand 0.41

Predicted protein targets (top 4)

geneUniProtsupporting neighboursconfidence
DPP7 Q9UHL4 13/20 0.40
DPP8 Q6V1X1 1/20 0.40
DPP4 P27487 5/20 0.39
HPGD P15428 1/20 0.37

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL11116325 1.00 DPP7 (0.40) DPP7DPP8DPP4HPGD
SCHEMBL11109056 0.96 DPP7 (0.37) DPP7DPP8DPP4
SCHEMBL11109060 0.96 DPP7 (0.37) DPP7DPP8DPP4
SCHEMBL15853678 0.86 DPP7 (0.41) DPP7DPP8DPP4
SCHEMBL15853681 0.84 DPP7 (0.43) DPP7DPP8DPP4
SCHEMBL8975358 0.84 DPP7 (0.43) DPP7DPP8DPP4
SCHEMBL11111091 0.83 DPP7 (0.39) DPP7DPP8DPP4HPGD
SCHEMBL11111088 0.83 DPP7 (0.39) DPP7DPP8DPP4HPGD
SCHEMBL11116004 0.82 DPP7 (0.40) DPP7DPP8DPP4
SCHEMBL20369058 0.82 CPN1 (0.37) DPP7DPP8DPP4

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0051682-B1 CYSTEINE DERIVATIVES AND PROCESS FOR THEIR PREPARATION MITSUBISHI KASEI CORPORATION (JP) 1984-09-05 EP disclosed
US-4440788-A REGENERATION OF LIVER CELLS MITSUBISHI CHEMICAL INDUSTRIES, LIMITED (JP) 1984-04-03 US disclosed
EP-0051682-A1 CYSTEINE DERIVATIVES AND PROCESS FOR THEIR PREPARATION MITSUBISHI KASEI CORPORATION (JP) 1982-05-19 EP disclosed