SCHEMBL8975358

SCHEMBL8975358

NC(CSSC[C@H](N)C(=O)N1CCCCC1)C(=O)N1CCCCC1

nearest known ligand 0.43

Predicted protein targets (top 4)

geneUniProtsupporting neighboursconfidence
DPP7 Q9UHL4 14/20 0.43
DPP8 Q6V1X1 1/20 0.40
DPP4 P27487 4/20 0.39
ALDH1A1 P00352 2/20 0.38

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL15853681 1.00 DPP7 (0.43) DPP7DPP8DPP4ALDH1A1
SCHEMBL15853678 0.98 DPP7 (0.41) DPP7DPP8DPP4ALDH1A1
SCHEMBL15853677 0.90 MEN1 (0.42) DPP7ALDH1A1
SCHEMBL11116325 0.84 DPP7 (0.40) DPP7DPP8DPP4
SCHEMBL11116329 0.84 DPP7 (0.40) DPP7DPP8DPP4
SCHEMBL11116008 0.82 DPP7 (0.40) DPP7DPP8DPP4ALDH1A1
SCHEMBL11116004 0.82 DPP7 (0.40) DPP7DPP8DPP4ALDH1A1
SCHEMBL23514532 0.81 DPP8 (0.49) DPP8
SCHEMBL23514531 0.81 DPP8 (0.49) DPP8
SCHEMBL23514439 0.81 CA2 (0.39) DPP7DPP4

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0705253-A1 ARALKYLAMINOQUINAZOLINES BAYER AG (DE) 1996-04-10 EP disclosed
WO-1995000496-A1 ARALKYLAMINOQUINAZOLINES BAYER AKTIENGESELLSCHAFT (DE) 1995-01-05 WO disclosed