Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NOTUM | Q6P988 | 15/20 | 0.39 |
| ▸ | TSHR | P16473 | 1/20 | 0.34 |
| ▸ | MAPT | P10636 | 2/20 | 0.33 |
| ▸ | TLR8 | Q9NR97 | 1/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.33 |
| ▸ | LMNA | P02545 | 1/20 | 0.33 |
| ▸ | HTT | P42858 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23716669 | 0.69 | — | — | |
| SCHEMBL12906161 | 0.69 | NOTUM (0.59) | NOTUMTSHRMAPTTLR8KDM4E | |
| SCHEMBL6306433 | 0.64 | NOTUM (0.39) | NOTUMTSHRMAPTTLR8ALDH1A1 | |
| SCHEMBL29683111 | 0.64 | KDM4E (0.59) | NOTUMMAPTTLR8KDM4EALDH1A1 | |
| SCHEMBL2746970 | 0.64 | KDM4E (0.59) | NOTUMMAPTTLR8KDM4EALDH1A1 | |
| SCHEMBL24921973 | 0.63 | MAPT (0.42) | NOTUMTSHRMAPTTLR8KDM4E | |
| SCHEMBL1178849 | 0.63 | NOTUM (0.42) | NOTUMMAPTKDM4EALDH1A1 | |
| SCHEMBL14401143 | 0.63 | NOTUM (0.44) | NOTUMTSHRMAPTKDM4EALDH1A1 | |
| SCHEMBL12446805 | 0.63 | NOTUM (0.66) | NOTUMTLR8KDM4E | |
| SCHEMBL440423 | 0.63 | NOTUM (0.42) | NOTUMTSHRMAPTTLR8KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0127847-A1 | 7-Oxo-4-thia-1-azabicyclo(3.2.0)hept-2-ene derivatives | HOECHST UK LIMITED (GB) | 1984-12-12 | — | — | EP | disclosed |