Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 8/20 | 0.59 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.59 |
| ▸ | NOTUM | Q6P988 | 7/20 | 0.53 |
| ▸ | LMNA | P02545 | 3/20 | 0.50 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.50 |
| ▸ | CCR1 | P32246 | 2/20 | 0.50 |
| ▸ | CCR5 | P51681 | 2/20 | 0.50 |
| ▸ | CCR8 | P51685 | 2/20 | 0.50 |
| ▸ | POLB | P06746 | 1/20 | 0.50 |
| ▸ | METAP1 | P53582 | 1/20 | 0.50 |
| ▸ | BLM | P54132 | 1/20 | 0.50 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.50 |
| ▸ | DOHH | Q9BU89 | 1/20 | 0.50 |
| ▸ | P4HTM | Q9NXG6 | 1/20 | 0.50 |
| ▸ | TP53 | P04637 | 4/20 | 0.48 |
| ▸ | NPC1 | O15118 | 4/20 | 0.48 |
| ▸ | RAB9A | P51151 | 4/20 | 0.48 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.48 |
| ▸ | HPGD | P15428 | 2/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29683111 | 1.00 | KDM4E (0.59) | KDM4ERXFP1NOTUMLMNACYP1A2 | |
| SCHEMBL12446805 | 0.75 | NOTUM (0.66) | KDM4ERXFP1NOTUMTLR8 | |
| SCHEMBL1178849 | 0.74 | NOTUM (0.42) | KDM4ERXFP1NOTUMALDH1A1HPGD | |
| SCHEMBL10553462 | 0.74 | KDM4E (0.59) | KDM4ELMNACYP1A2CCR1CCR5 | |
| SCHEMBL28394924 | 0.74 | NOTUM (0.50) | KDM4ERXFP1NOTUMTLR8 | |
| Dipyridyl SCHEMBL18229257 | 0.72 | KDM4E (0.93) | KDM4ELMNACYP1A2CCR1CCR5 | |
| Dipyridyl SCHEMBL8993652 | 0.72 | KDM4E (0.93) | KDM4ELMNACYP1A2CCR1CCR5 | |
| SCHEMBL6051817 | 0.72 | NOTUM (0.41) | KDM4ERXFP1NOTUMNPC1RAB9A | |
| Dipyridyl SCHEMBL3711450 | 0.69 | KDM4E (1.00) | KDM4ELMNACYP1A2CCR1CCR5 | |
| SCHEMBL12906161 | 0.69 | NOTUM (0.59) | KDM4ENOTUMLMNAALDH1A1HPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 39 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2619190-A1 | SUBSTITUTED OXADIAZOLE COMPOUNDS AND THEIR USE AS S1P1 AGONISTS | Bristol-Myers Squibb Company (US) | 2013-07-31 | — | — | EP | claimed |
| WO-2012040532-A1 | SUBSTITUTED OXADIAZOLE COMPOUNDS AND THEIR USE AS S1P1 AGONISTS | BRISTOL-MYERS SQUIBB COMPANY (US) | 2012-03-29 | — | — | WO | claimed |
| US-20250262201-A1 | COMPOUNDS AND METHODS USEFUL FOR STABILIZING PHENYLALANINE HYDROXYLASE MUTATIONS | AGIOS PHARMACEUTICALS, INC. | 2025-08-21 | — | — | US | disclosed |
| WO-2023164236-A1 | COMPOUNDS AND METHODS USEFUL FOR STABILIZING PHENYLALANINE HYDROXYLASE MUTATIONS | AGIOS PHARMACEUTICALS, INC. (US) | 2023-08-31 | — | — | WO | disclosed |
| WO-2023164236-A1 | COMPOUNDS AND METHODS USEFUL FOR STABILIZING PHENYLALANINE HYDROXYLASE MUTATIONS | AGIOS PHARMACEUTICALS, INC. (US) | 2023-08-31 | — | — | WO | disclosed |
| US-20220119434-A1 | ORGANIC ELECTROLUMINESCENT MATERIALS AND DEVICES | UNIVERSAL DISPLAY CORPORATION (US) | 2022-04-21 | — | — | US | disclosed |
| CN-111072842-B | Water-soluble fluorescent polymer containing pyridyl 1,3, 4-oxadiazole and synthetic method thereof | 山东泰和水处理科技股份有限公司 | 2021-12-10 | — | — | CN | disclosed |
| CN-111072842-B | Water-soluble fluorescent polymer containing pyridyl 1,3, 4-oxadiazole and synthetic method thereof | 山东泰和水处理科技股份有限公司 | 2021-12-10 | — | — | CN | disclosed |
| CN-111072842-B | Water-soluble fluorescent polymer containing pyridyl 1,3, 4-oxadiazole and synthetic method thereof | 山东泰和水处理科技股份有限公司 | 2021-12-10 | — | — | CN | disclosed |
| US-20210167302-A1 | ORGANIC ELECTROLUMINESCENT MATERIALS AND DEVICES | UNIVERSAL DISPLAY CORPORATION (US) | 2021-06-03 | — | — | US | disclosed |
| US-10975113-B2 | Organic electroluminescent materials and devices | UNIVERSAL DISPLAY CORPORATION (US) | 2021-04-13 | — | — | US | disclosed |
| EP-2252609-A1 | PYRIDIN-2-YL DERIVATIVES AS IMMUNOMODULATING AGENTS | Actelion Pharmaceuticals Ltd. (CH) | 2010-11-24 | — | — | EP | disclosed |
| EP-1979345-B1 | NOVEL PYRIDINE DERIVATIVES | ACTELION PHARMACEUTICALS LTD (CH) | 2009-11-04 | — | — | EP | disclosed |
| US-20090264653-A1 | USEFUL INDOLE COMPOUNDS | IRONWOOD PHARMACEUTICALS, INC. | 2009-10-22 | — | — | US | disclosed |
| WO-2009109872-A1 | PYRIDIN-2-YL DERIVATIVES AS IMMUNOMODULATING AGENTS | ACTELION PHARMACEUTICALS LTD (CH) | 2009-09-11 | — | — | WO | disclosed |
| US-20090005421-A1 | Novel Pyridine Derivatives | ACTELION PHARMACEUTICALS LTD. (CH) | 2009-01-01 | — | — | US | disclosed |
| EP-1979345-A2 | NOVEL PYRIDINE DERIVATIVES | Actelion Pharmaceuticals Ltd. (CH) | 2008-10-15 | — | — | EP | disclosed |
| WO-2007086001-A2 | NOVEL PYRIDINE DERIVATIVES | ACTELION PHARMACEUTICALS LTD (CH) | 2007-08-02 | — | — | WO | disclosed |
| US-20070105866-A1 | 5-LIPOXYGENASE-ACTIVATING PROTEIN (FLAP) INHIBITORS | AMIRA PHARMACEUTICALS, INC. (US) | 2007-05-10 | — | — | US | disclosed |
| EP-0116515-B1 | PESTICIDE | CIBA-GEIGY AG (CH) | 1988-09-21 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (6 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20250262201-A1 | COMPOUNDS AND METHODS USEFUL FOR STABILIZING PHENYLALANINE HYDROXYLASE MUTATIONS | PAH, KDM8, PHF8 | KDM4E 104/4885RXFP1 951/4885NOTUM 1909/4885 |
| US-20070105866-A1 | 5-LIPOXYGENASE-ACTIVATING PROTEIN (FLAP) INHIBITORS | ALOX5, ALOX15B, ALOX15 | KDM4E 2621/4885RXFP1 2686/4885NOTUM 185/4885 |
| US-20220119434-A1 | ORGANIC ELECTROLUMINESCENT MATERIALS AND DEVICES | L1CAM, SOD1, EPCAM | KDM4E 4057/4885RXFP1 3729/4885NOTUM 3585/4885 |
| US-10975113-B2 | Organic electroluminescent materials and devices | OSBPL3, OCIAD1, OSBP | KDM4E 4617/4885RXFP1 4272/4885NOTUM 1026/4885 |
| US-20090005421-A1 | Novel Pyridine Derivatives | NFATC1, TPMT, CD47 | KDM4E 708/4885RXFP1 2711/4885NOTUM 4660/4885 |
| US-20090264653-A1 | USEFUL INDOLE COMPOUNDS | FAAH, FAAH2, AANAT | KDM4E 2232/4885RXFP1 1724/4885NOTUM 408/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.